(FFO)  Miami (FL) v.  Drake | 11:00 AM | |
(11)  VCU v.  Seton Hall | 4:00 PM | ESPN2 |
 UNCG @ (8)  Indiana | 5:30 PM | FS1 |
(3)  Baylor v. (5)  Saint John's | 6:00 PM | |
(7)  Texas v.  Syracuse | 6:00 PM | ESPN2 |
 Radford @ (FFO)  Clemson | 6:00 PM | ACC Extra |
(9)  Nevada v.  Vanderbilt | 6:30 PM | ESPNU |
 Oral Roberts @ (11)  Ole Miss | 7:00 PM | SECN+ |
 East Texas A&M @ (FFO)  Oklahoma | 7:00 PM | SECN+ |
(12)  Princeton v.  Wright State | 7:00 PM | ESPN+ |
 Tarleton State @ (8)  Michigan | 7:30 PM | BTN |
(3)  Texas Tech v.  Saint Joseph's | 8:00 PM | ESPN2 |
(2)  Tennessee v.  Virginia | 8:30 PM | |
(8)  Oregon @  Oregon State | 9:00 PM | ESPN+ |
(9)  Memphis @ (NFO)  San Francisco | 9:00 PM | |
(6)  Pittsburgh v. (10)  LSU | 1:30 PM | |
(7)  Wisconsin v.  UCF | 4:00 PM | CBSSN |
 Utah Tech @ (NFO)  Utah | 4:30 PM | ESPN+ |
(12)  Liberty v.  Louisiana | 4:30 PM | ESPN+ |
 Campbell @ (6)  Ohio State | 5:00 PM | BTN |
 Jackson State @ (3)  Kentucky | 6:00 PM | SECN+ |
 Southern Illinois @ (6)  Florida | 6:00 PM | SEC Network |
 William & Mary @ (FFO)  North Carolina State | 6:00 PM | ACC Extra |
 Elon @ (NFO)  Notre Dame | 6:30 PM | ACC Extra |
 Hofstra @ (1)  Houston | 7:00 PM | ESPN+ |
 Nebraska @ (5)  Creighton | 7:00 PM | FS1 |
(11)  Iowa v. (11)  Utah State | 7:00 PM | BTN |
(7)  Mississippi State @  SMU | 7:30 PM | ACC Extra |
 Little Rock @ (9)  Arkansas | 8:00 PM | SEC Network |
(12)  UC Irvine @  Weber State | 8:00 PM | ESPN+ |
(15)  Norfolk State @ (12)  Grand Canyon | 8:00 PM | ESPN+ |
 Cal State Fullerton @ (8)  UCLA | 9:00 PM | BTN |
(2)  Duke @ (5)  Arizona | 9:30 PM | ESPN2 |
(4)  North Carolina @  Hawaii | 10:59 PM | ESPN2 |
(2)  Connecticut v. (9) Memphis | 1:30 PM | ESPN2 |
(10)  Penn State v.  Fordham | 3:00 PM | CBSSN |
(10)  Michigan State v.  Colorado | 4:00 PM | ESPN2 |
(8) Michigan v.  Virginia Tech | 5:00 PM | FS1 |
| (FFO) Clemson v. (NFO) San Francisco | 5:30 PM | |
 Green Bay @ (6) Ohio State | 7:00 PM | BTN |
 Maryland Eastern Shore @ (9) Arkansas | 7:00 PM | SECN+ |
(11)  Xavier v.  South Carolina | 7:30 PM | FS1 |
(1)  Auburn v. (2)  Iowa State | 8:00 PM | ESPNU |
Little Rock @ (6)  Illinois | 8:00 PM | BTN |
(4) North Carolina v. (NFO)  Dayton | 10:30 PM | ESPN2 |
(8) Indiana v.  Louisville | 11:00 AM | ESPN |
 New Orleans @ (3) Baylor | 1:00 PM | ESPN+ |
(1)  Gonzaga v.  West Virginia | 1:30 PM | ESPN |
 Tennessee-Martin @ (2) Tennessee | 3:00 PM | SECN+ |
(8) Oregon v.  San Diego State | 3:00 PM | Max |
(16)  Bucknell @ (10)  Maryland | 3:30 PM | BTN |
(FFO) Oklahoma v.  Providence | 4:00 PM | ESPN2 |
(5)  Texas A&M v. (5) Creighton | 5:30 PM | Max |
 Alabama State @ (3)  Cincinnati | 6:00 PM | ESPN+ |
(5) Arizona v.  Davidson | 6:30 PM | ESPN2 |
 Stonehill @ (4)  Marquette | 8:00 PM | |
(4)  Alabama v.  Rutgers | 9:00 PM | TBS |
| (1) Houston v. (NFO) Notre Dame | 10:59 PM | |
| Syracuse @ (2) Tennessee | 0:00 | |
| (9) Arkansas @ (FFO) Miami (FL) | 0:00 | |
(3) Cincinnati @  Villanova | 5:30 PM | FS1 |
 Northwestern @ (11) Iowa | 6:00 PM | Peacock |
 Western Michigan @ (NFO) Dayton | 6:00 PM | ESPN+ |
(NFO) Notre Dame @  Georgia | 6:00 PM | ESPNU |
| (12) Princeton @ Saint Joseph's | 6:00 PM | ESPN+ |
 Sam Houston State @ (8) Indiana | 6:30 PM | BTN |
(7)  BYU @ Providence | 7:30 PM | FS1 |
 Wake Forest @ (5) Texas A&M | 8:00 PM | ESPN2 |
| (8) Michigan @ (7) Wisconsin | 8:00 PM | Peacock |
 Florida State @ (10) LSU | 8:00 PM | SEC Network |
Utah Tech @ (11)  Boise State | 8:00 PM | |
| (11) Ole Miss @ Louisville | 8:00 PM | ACC Network |
 Georgia Tech @ (FFO) Oklahoma | 8:00 PM | ESPNU |
| Hawaii @ (12) Grand Canyon | 8:00 PM | ESPN+ |
| (3) Kentucky @ (FFO) Clemson | 8:30 PM | ESPN |
 UTSA @ (9)  Saint Mary's College | 9:00 PM | ESPN+ |
 Washington @ (8) UCLA | 9:30 PM | FS1 |
 Louisiana Tech @ (9) Memphis | 0:00 | |
| (3) Baylor @ (2) Connecticut | 5:30 PM | FS1 |
| (6) Ohio State @ (10) Maryland | 5:30 PM | BTN |
 Georgia Southern @ (11) VCU | 6:00 PM | ESPN+ |
| (4) Alabama @ (4) North Carolina | 6:15 PM | ESPN |
| Virginia @ (6) Florida | 6:15 PM | ESPN2 |
| (4) Marquette @ (2) Iowa State | 7:00 PM | |
(1)  Kansas @ (5) Creighton | 7:30 PM | FS1 |
(10) Michigan State @  Minnesota | 7:30 PM | BTN |
 Wyoming @ (11) Utah State | 8:00 PM | |
| (1) Auburn @ (2) Duke | 8:15 PM | ESPN |
 DePaul @ (3) Texas Tech | 8:15 PM | ESPNU |
| (6) Pittsburgh @ (7) Mississippi State | 8:15 PM | SEC Network |
| (7) Texas @ (FFO) North Carolina State | 8:15 PM | ESPN2 |
(8) Oregon @  USC | 9:30 PM | BTN |
 Kansas State @ (5) Saint John's | 10:30 AM | FOX |
| Rutgers @ (6) Ohio State | 11:00 AM | FS1 |
| Nebraska @ (10) Michigan State | 11:00 AM | BTN |
| (FFO) Clemson @ (FFO) Miami (FL) | 11:00 AM | ESPN2 |
| Syracuse @ (NFO) Notre Dame | 11:00 AM | |
(12) Princeton @ (15)  Furman | 11:00 AM | ESPN+ |
| (7) Wisconsin @ (4) Marquette | 12:30 PM | FOX |
| Georgia Tech @ (4) North Carolina | 1:00 PM | ACC Network |
 Southern Utah @ (5) Arizona | 1:00 PM | CBSSN |
| (6) Pittsburgh @ Virginia Tech | 1:00 PM | ESPNU |
| (11) Iowa @ (8) Michigan | 1:00 PM | FS1 |
 Lehigh @ (NFO) Dayton | 1:00 PM | ESPN+ |
 UNLV @ (5) Creighton | 3:00 PM | FS1 |
| Florida State @ (FFO) North Carolina State | 3:00 PM | ESPNU |
(11) Boise State v.  Washington State | 4:00 PM | |
 Butler @ (1) Houston | 4:30 PM | ESPN2 |
| (9) Saint Mary's College @ (NFO) Utah | 6:00 PM | ESPN+ |
 Mississippi Valley State @ (12) Liberty | 6:00 PM | ESPN+ |
| UTSA @ (9) Arkansas | 7:00 PM | SECN+ |
 Lindenwood @ (11) Ole Miss | 7:00 PM | SECN+ |
 Alcorn State @ (FFO) Oklahoma | 7:00 PM | SECN+ |
(9) Nevada @  Loyola-Marymount | 8:00 PM | ESPN+ |
| Utah Tech @ (11) Utah State | 8:00 PM | |
| (3) Kentucky @ (1) Gonzaga | 9:00 PM | ESPN2 |
| (9) Saint Mary's College v. (11) Boise State | 0:00 | |
| (9) Memphis @ (FFO) Clemson | 10:00 AM | ESPN2 |
(4)  Purdue v. (5) Texas A&M | 11:00 AM | CBS |
 Coppin State @ (10) Penn State | 11:30 AM | BTN |
| (1) Auburn v. (6) Ohio State | 12:00 PM | ESPN2 |
| (11) Xavier @ (3) Cincinnati | 1:00 PM | ESPN+ |
| (7) Wisconsin v. Butler | 1:30 PM | BTN |
| (5) Arizona v. (8) UCLA | 2:00 PM | ESPN2 |
| (FFO) North Carolina State @ (1) Kansas | 2:15 PM | ESPN |
(6) Florida v.  Arizona State | 2:30 PM | SEC Network |
 La Salle @ (4) North Carolina | 3:00 PM | |
 Central Arkansas @ (9) Arkansas | 3:00 PM | SECN+ |
| (10) LSU v. SMU | 3:00 PM | ESPNU |
 South Florida @ (11) Utah State | 3:00 PM | |
(11) Ole Miss v.  Southern Miss | 3:00 PM | |
| (12) UC Irvine @ Oregon State | 4:00 PM | ESPN+ |
| Louisville @ (3) Kentucky | 4:15 PM | ESPN |
| (2) Tennessee @ (6) Illinois | 4:30 PM | FOX |
(7) Mississippi State v. (13)  McNeese | 5:00 PM | ESPNU |
| (12) Grand Canyon v. Georgia | 5:00 PM | SEC Network |
| (4) Marquette @ (NFO) Dayton | 6:00 PM | CBSSN |
| Radford @ (NFO) Utah | 6:00 PM | ESPN+ |
 North Carolina A&T @ (12) Liberty | 6:00 PM | ESPN+ |
(11) VCU v.  Colorado State | 6:30 PM | |
| (1) Gonzaga v. (2) Connecticut | 7:00 PM | FOX |
(FFO) Oklahoma v.  Oklahoma State | 7:00 PM | ESPNU |
| (5) Creighton @ (4) Alabama | 7:30 PM | SEC Network |
| Wyoming @ (7) BYU | 8:00 PM | |
 Texas Southern @ (9) Nevada | 9:00 PM | |
| DePaul @ (5) Saint John's | 5:30 PM | Peacock |
 Western Carolina @ (2) Tennessee | 6:00 PM | SECN+ |
 George Mason @ (2) Duke | 6:00 PM | ACC Network |
| (4) North Carolina v. (6) Florida | 6:00 PM | ESPN |
(10) Michigan State v.  Oakland | 6:00 PM | ESPN2 |
 Southern @ (11) Ole Miss | 6:00 PM | SECN+ |
| (FFO) Clemson @ South Carolina | 6:00 PM | SEC Network |
| UNLV @ (NFO) Dayton | 6:00 PM | |
(7) Mississippi State v.  Central Michigan | 6:30 PM | SECN+ |
 Saint Francis (PA) @ (10) Maryland | 6:30 PM | BTN |
 Georgia State @ (1) Auburn | 7:00 PM | SECN+ |
 Valparaiso @ (6) Ohio State | 7:00 PM | Peacock |
 Stetson @ (10) LSU | 8:00 PM | SEC Network |
| Texas Southern @ (11) Boise State | 8:00 PM | |
 UC San Diego @ (11) Utah State | 8:00 PM | |
 Florida A&M @ (NFO) Utah | 8:00 PM | ESPN+ |
 Prairie View A&M @ (8) UCLA | 8:30 PM | BTN |
| (2) Duke @ Georgia Tech | 0:00 | ACC Network |
| (2) Connecticut @ Butler | 11:00 AM | Peacock |
| (4) Marquette @ (11) Xavier | 11:00 AM | FOX |
 North Florida @ (6) Florida | 11:00 AM | SEC Network |
 Chattanooga @ (8) Indiana | 11:00 AM | BTN |
(10) Penn State @  Drexel | 11:00 AM | |
| (10) Maryland v. Syracuse | 11:00 AM | ESPN2 |
| (12) Princeton v. Rutgers | 11:00 AM | FS1 |
| (7) Mississippi State @ (9) Memphis | 11:30 AM | |
 Lamar @ (3) Texas Tech | 12:00 PM | ESPN+ |
| Sam Houston State @ (6) Pittsburgh | 12:00 PM | ACC Extra |
 Texas A&M-Corpus Christi @ (1) Houston | 1:00 PM | CBSSN |
 FAU @ (10) Michigan State | 1:00 PM | FS1 |
 Mount Saint Mary's @ (FFO) Miami (FL) | 1:00 PM | ACC Extra |
 UTA @ (12) Liberty | 1:00 PM | ESPN+ |
| North Carolina A&T @ (9) Arkansas | 1:30 PM | SEC Network |
| Wake Forest @ (FFO) Clemson | 1:30 PM | ESPN |
(12) UC Irvine @  Duquesne | 1:30 PM | ESPN+ |
| (4) North Carolina v. (8) UCLA | 2:00 PM | CBS |
 Air Force @ (11) Boise State | 2:30 PM | |
| Central Michigan @ (5) Arizona | 3:00 PM | ESPN+ |
| Villanova @ (5) Creighton | 3:00 PM | FS1 |
| (1) Auburn v. (4) Purdue | 3:30 PM | ESPN |
| Colorado State @ (9) Nevada | 4:00 PM | |
| (3) Kentucky v. (6) Ohio State | 4:30 PM | CBS |
| (11) Iowa v. (NFO) Utah | 5:00 PM | BTN |
 Montana @ (NFO) San Francisco | 5:00 PM | ESPN+ |
 Queens @ (11) Ole Miss | 6:00 PM | SECN+ |
(8) Oregon v.  Stanford | 7:00 PM | BTN |
| (16) Bucknell @ (1) Gonzaga | 8:00 PM | ESPN+ |
 Morgan State @ (2) Iowa State | 12:00 PM | ESPN+ |
(14)  Kent State @ (4) Alabama | 12:00 PM | SEC Network |
(6) Illinois v.  Missouri | 12:00 PM | ESPN |
(14)  Purdue Fort Wayne @ (8) Michigan | 12:00 PM | BTN+ |
| Central Arkansas @ (FFO) Oklahoma | 12:00 PM | SEC Network |
(16)  Grambling State @ (3) Cincinnati | 1:00 PM | ESPN+ |
 Detroit @ (7) Wisconsin | 1:00 PM | BTN |
| William & Mary @ (11) VCU | 1:00 PM | ESPN+ |
 Brown @ (1) Kansas | 2:00 PM | ESPN |
| New Orleans @ (10) LSU | 2:00 PM | SECN+ |
 Rider @ (FFO) North Carolina State | 3:00 PM | ACC Network |
 Saint Louis @ (12) Grand Canyon | 3:00 PM | ESPN+ |
 Le Moyne @ (NFO) Notre Dame | 5:00 PM | ACC Network |
| (11) Utah State @ (9) Saint Mary's College | 7:00 PM | ESPN+ |
| (1) Gonzaga v. (8) UCLA | 0:00 | FOX |
(11) Boise State @  San Jose State | 0:00 | |
| (11) Utah State @ San Diego State | 0:00 | |
(12) Grand Canyon v.  San Diego | 0:00 | |
| Maryland Eastern Shore @ (10) Maryland | 11:00 AM | BTN |
| (11) Ole Miss @ (9) Memphis | 1:00 PM | ESPN2 |
 Abilene Christian @ (5) Texas A&M | 3:00 PM | SEC Network |
| (9) Nevada @ Wyoming | 3:00 PM | |
| Loyola-Marymount @ (NFO) San Francisco | 4:00 PM | ESPN+ |
 Delaware @ (5) Saint John's | 5:00 PM | FS1 |
 Pacific @ (9) Saint Mary's College | 7:00 PM | ESPN+ |
 Akron @ (12) Princeton | 12:00 PM | ESPN+ |
| Western Michigan @ (10) Michigan State | 2:00 PM | BTN |
 Monmouth @ (1) Auburn | 5:30 PM | SECN+ |
| (3) Cincinnati @ Kansas State | 6:00 PM | ESPN+ |
 New Hampshire @ (11) Iowa | 6:00 PM | BTN |
| (1) Houston @ Oklahoma State | 7:00 PM | ESPN+ |
 TCU @ (5) Arizona | 7:00 PM | ESPN+ |
| Oakland @ (9) Arkansas | 7:00 PM | ESPNU |
 Bryant @ (12) Grand Canyon | 7:00 PM | ESPN+ |
| (2) Iowa State @ Colorado | 8:00 PM | CBSSN |
 Bethune-Cookman @ (7) Mississippi State | 8:00 PM | SEC Network |
(1) Gonzaga @  Pepperdine | 9:00 PM | ESPN+ |
 Santa Clara @ (NFO) San Francisco | 9:00 PM | ESPN+ |
(12) UC Irvine @  California Baptist | 9:00 PM | ESPN+ |
| West Virginia @ (1) Kansas | 0:00 | ESPN+ |
| (FFO) North Carolina State @ Virginia | 11:00 AM | ESPN2 |
| (NFO) Utah @ (3) Baylor | 1:00 PM | ESPN+ |
| UCF @ (3) Texas Tech | 1:00 PM | ESPN+ |
| Brown @ (3) Kentucky | 1:00 PM | ESPNU |
(11) VCU @  Saint Bonaventure | 1:00 PM | ESPN+ |
| Seton Hall @ (11) Xavier | 1:00 PM | Peacock |
| La Salle @ (NFO) Dayton | 1:00 PM | ESPN+ |
| (NFO) Notre Dame @ Georgia Tech | 1:30 PM | ACC Network |
| (15) Norfolk State @ (2) Tennessee | 2:00 PM | SECN+ |
| (5) Saint John's @ (5) Creighton | 3:00 PM | Peacock |
| Arizona State @ (7) BYU | 3:00 PM | ESPN2 |
| Virginia Tech @ (2) Duke | 3:30 PM | ACC Network |
| (4) Marquette @ Providence | 5:00 PM | FS1 |
| (11) Boise State @ Wyoming | 7:30 PM | |
| (11) Utah State @ (9) Nevada | 9:00 PM | |
| (1) Gonzaga @ Loyola-Marymount | 0:00 | |
(9) Saint Mary's College @  Portland | 0:00 | |
| Southern Utah @ (12) Grand Canyon | 0:00 | |
| (6) Florida @ (3) Kentucky | 10:00 AM | ESPN |
| (4) North Carolina @ (NFO) Notre Dame | 11:00 AM | |
| Georgia @ (11) Ole Miss | 11:00 AM | SEC Network |
| (FFO) North Carolina State @ Wake Forest | 11:00 AM | |
(NFO) Dayton @  George Washington | 11:00 AM | |
| (9) Arkansas @ (2) Tennessee | 12:00 PM | ESPN |
| (7) BYU @ (1) Houston | 1:00 PM | ESPN+ |
| (3) Baylor @ (2) Iowa State | 1:00 PM | CBS |
| Butler @ (5) Saint John's | 1:00 PM | FS1 |
| South Carolina @ (7) Mississippi State | 1:00 PM | SEC Network |
| (8) UCLA @ Nebraska | 1:00 PM | FOX |
(11) VCU @  Loyola-Chicago | 1:00 PM | |
| (FFO) Miami (FL) @ Virginia Tech | 1:00 PM | ACC Network |
| (2) Duke @ SMU | 1:15 PM | |
| (5) Arizona @ (3) Cincinnati | 1:30 PM | ESPN2 |
| Missouri @ (1) Auburn | 3:00 PM | SEC Network |
| San Diego State @ (11) Boise State | 3:00 PM | |
| Vanderbilt @ (10) LSU | 3:30 PM | ESPN2 |
| (FFO) Oklahoma @ (4) Alabama | 5:00 PM | SEC Network |
 Middle Tennessee @ (12) Liberty | 5:00 PM | CBSSN |
| Stanford @ (6) Pittsburgh | 5:30 PM | ESPN2 |
| (3) Texas Tech @ (NFO) Utah | 6:00 PM | ESPN+ |
| (NFO) San Francisco @ Washington State | 6:00 PM | |
| (7) Texas @ (5) Texas A&M | 7:00 PM | SEC Network |
| (8) Michigan @ USC | 7:00 PM | FOX |
 California @ (FFO) Clemson | 7:30 PM | ESPN2 |
 Fresno State @ (11) Utah State | 8:00 PM | |
 UC Riverside @ (12) UC Irvine | 9:00 PM | |
| (11) Utah State @ San Jose State | 0:00 | |
| (5) Saint John's @ (11) Xavier | 5:30 PM | FS1 |
| (2) Tennessee @ (6) Florida | 6:00 PM | |
| (6) Pittsburgh @ (2) Duke | 6:00 PM | ESPN |
| (3) Kentucky @ Georgia | 6:00 PM | SEC Network |
| (5) Arizona @ West Virginia | 6:00 PM | ESPN+ |
| (FFO) Clemson @ Louisville | 6:00 PM | |
| (NFO) Utah @ (2) Iowa State | 7:00 PM | ESPN+ |
| (3) Cincinnati @ (3) Baylor | 7:00 PM | ESPN+ |
 Georgetown @ (4) Marquette | 7:00 PM | CBSSN |
| Nebraska @ (11) Iowa | 7:00 PM | Peacock |
| (1) Auburn @ (7) Texas | 8:00 PM | |
| (3) Texas Tech @ (7) BYU | 8:00 PM | ESPN+ |
| SMU @ (4) North Carolina | 8:00 PM | ACC Network |
| (7) Mississippi State @ Vanderbilt | 8:00 PM | |
| (10) LSU @ Missouri | 8:00 PM | SEC Network |
| (8) Michigan @ (8) UCLA | 9:00 PM | Peacock |
| UNLV @ (11) Boise State | 9:30 PM | |
| Loyola-Marymount @ (9) Saint Mary's College | 10:00 PM | ESPN2 |
| (9) Saint Mary's College @ San Diego | 0:00 | |
| (NFO) Notre Dame @ (2) Duke | 11:00 AM | ESPN |
| (5) Creighton @ Butler | 11:00 AM | FOX |
| Louisville @ (6) Pittsburgh | 11:00 AM | ESPN2 |
| USC @ (6) Illinois | 11:00 AM | BTN |
| (1) Auburn @ South Carolina | 12:00 PM | SEC Network |
| (1) Kansas @ (3) Cincinnati | 1:00 PM | ESPN+ |
| (2) Connecticut @ Georgetown | 1:00 PM | |
| (2) Iowa State @ (3) Texas Tech | 1:00 PM | |
| (7) BYU @ TCU | 1:00 PM | |
 East Carolina @ (9) Memphis | 1:00 PM | |
| Florida State @ (FFO) Clemson | 1:00 PM | ACC Network |
(12) Princeton @  Harvard | 1:00 PM | |
| (4) North Carolina @ (FFO) North Carolina State | 3:00 PM | ACC Network |
| (6) Florida @ (9) Arkansas | 3:00 PM | |
| (11) Xavier @ DePaul | 3:00 PM | FS1 |
| Wake Forest @ (FFO) Miami (FL) | 4:15 PM | |
| (1) Houston @ Kansas State | 5:00 PM | ESPN+ |
| (2) Tennessee @ (7) Texas | 5:00 PM | |
| (10) LSU @ (11) Ole Miss | 5:00 PM | SEC Network |
| (FFO) Oklahoma @ Georgia | 5:00 PM | |
| Villanova @ (5) Saint John's | 6:00 PM | CBSSN |
| (9) Nevada @ Fresno State | 6:00 PM | |
| (NFO) San Francisco @ Santa Clara | 6:00 PM | |
| Oklahoma State @ (NFO) Utah | 6:00 PM | ESPN+ |
| (4) Alabama @ (5) Texas A&M | 7:00 PM | |
| (8) Indiana @ (11) Iowa | 7:00 PM | FOX |
| (12) Liberty @ Louisiana Tech | 7:00 PM | ESPNU |
| (3) Kentucky @ (7) Mississippi State | 7:30 PM | SEC Network |
| Washington State @ (1) Gonzaga | 8:00 PM | |
| (11) Boise State @ (11) Utah State | 8:00 PM | |
| (3) Baylor @ Arizona State | 8:30 PM | ESPN+ |
| UCF @ (5) Arizona | 9:00 PM | ESPN |
| (12) UC Irvine @ UC San Diego | 9:00 PM | |
| Villanova @ (11) Xavier | 5:30 PM | FS1 |
| (7) Mississippi State @ (1) Auburn | 6:00 PM | SEC Network |
| (5) Texas A&M @ (3) Kentucky | 6:00 PM | |
| (11) Ole Miss @ (4) Alabama | 6:00 PM | |
| (4) Marquette @ DePaul | 6:00 PM | CBSSN |
| (6) Illinois @ (8) Indiana | 6:00 PM | Peacock |
| Saint Louis @ (11) VCU | 6:00 PM | |
| Georgetown @ (5) Saint John's | 6:30 PM | Peacock |
| Providence @ (5) Creighton | 7:30 PM | FS1 |
| (FFO) Miami (FL) @ (2) Duke | 8:00 PM | ESPN |
| (3) Texas Tech @ Kansas State | 8:00 PM | CBSSN |
| Missouri @ (6) Florida | 8:00 PM | ESPNU |
| (6) Ohio State @ (7) Wisconsin | 8:00 PM | Peacock |
| Oklahoma State @ (7) BYU | 8:00 PM | ESPN+ |
| (9) Arkansas @ (10) LSU | 8:00 PM | SEC Network |
| Wyoming @ (11) Boise State | 8:00 PM | |
| (FFO) Clemson @ Georgia Tech | 8:00 PM | ACC Network |
| Air Force @ (9) Nevada | 9:00 PM | |
| (11) Iowa @ USC | 9:30 PM | FS1 |
| (3) Baylor @ (5) Arizona | 10:00 PM | ESPN |
| (1) Kansas @ (2) Iowa State | 6:00 PM | ESPN2 |
| California @ (4) North Carolina | 6:00 PM | ACC Network |
| (FFO) North Carolina State @ Virginia Tech | 6:00 PM | ESPNU |
| George Mason @ (NFO) Dayton | 6:00 PM | |
| (10) Penn State @ (10) Michigan State | 6:30 PM | BTN |
| West Virginia @ (1) Houston | 7:00 PM | ESPN+ |
| Georgia @ (2) Tennessee | 7:00 PM | SEC Network |
| (NFO) Utah @ TCU | 7:00 PM | ESPN+ |
| (3) Cincinnati @ Colorado | 8:00 PM | ESPN+ |
| (6) Pittsburgh @ Florida State | 8:00 PM | ESPNU |
| (4) Purdue @ Washington | 8:30 PM | BTN |
| (7) Texas @ (FFO) Oklahoma | 9:00 PM | SEC Network |
| (11) Utah State @ UNLV | 10:00 PM | |
(2) Duke @  Boston College | 0:00 | |
| (5) Arizona @ (3) Texas Tech | 0:00 | |
| (7) Texas @ (6) Florida | 0:00 | |
| (11) Ole Miss @ (7) Mississippi State | 0:00 | |
| (9) Saint Mary's College @ Pepperdine | 0:00 | |
| South Carolina @ (FFO) Oklahoma | 0:00 | |
| SMU @ (FFO) Miami (FL) | 0:00 | |
| Tarleton State @ (12) Grand Canyon | 0:00 | |
| (1) Houston @ UCF | 11:00 AM | CBSSN |
| (5) Creighton @ (2) Connecticut | 11:00 AM | FOX |
| (4) Alabama @ (3) Kentucky | 11:00 AM | ESPN |
| (FFO) Clemson @ (6) Pittsburgh | 11:00 AM | |
| (1) Auburn @ Georgia | 12:00 PM | SEC Network |
| Kansas State @ (1) Kansas | 12:00 PM | CBS |
| Arizona State @ (3) Cincinnati | 1:00 PM | CBSSN |
| (11) Xavier @ (4) Marquette | 1:00 PM | FOX |
(12) Princeton @  Dartmouth | 1:00 PM | |
| Stanford @ (4) North Carolina | 1:15 PM | |
| (4) Purdue @ (8) Oregon | 2:00 PM | NBC |
| (7) Wisconsin @ USC | 2:00 PM | BTN |
| (2) Tennessee @ Vanderbilt | 2:30 PM | SEC Network |
| Loyola-Chicago @ (NFO) Dayton | 3:00 PM | |
| (NFO) Notre Dame @ Syracuse | 3:00 PM | ACC Network |
| (2) Iowa State @ West Virginia | 4:00 PM | ESPN+ |
| San Jose State @ (9) Nevada | 5:00 PM | |
| (9) Arkansas @ Missouri | 5:00 PM | SEC Network |
| California @ (FFO) North Carolina State | 5:00 PM | ACC Network |
 New Mexico State @ (12) Liberty | 6:00 PM | ESPN+ |
| (5) Saint John's @ Seton Hall | 7:00 PM | |
| (10) LSU @ (5) Texas A&M | 7:30 PM | SEC Network |
| Santa Clara @ (1) Gonzaga | 8:00 PM | |
| (7) BYU @ (NFO) Utah | 8:00 PM | ESPN+ |
| Oregon State @ (NFO) San Francisco | 9:00 PM | |
 Cal Poly @ (12) UC Irvine | 9:00 PM | |
| (1) Gonzaga @ Portland | 0:00 | |
| (6) Pittsburgh @ Syracuse | 11:00 AM | |
| SMU @ (FFO) North Carolina State | 11:00 AM | |
| (7) Mississippi State @ South Carolina | 12:00 PM | SEC Network |
| Seton Hall @ (5) Creighton | 12:30 PM | FS1 |
| (10) Michigan State @ Rutgers | 12:30 PM | CBS |
| (2) Iowa State @ Arizona State | 1:00 PM | ESPN+ |
 Cornell @ (12) Princeton | 1:00 PM | |
| Boston College @ (4) North Carolina | 1:15 PM | |
| (3) Kentucky @ Vanderbilt | 1:30 PM | |
| (5) Texas A&M @ (7) Texas | 1:30 PM | |
| Colorado @ (5) Arizona | 2:00 PM | ESPN+ |
| Georgia @ (6) Florida | 2:30 PM | SEC Network |
| (8) Oregon @ Minnesota | 3:00 PM | BTN |
| (11) Utah State @ Air Force | 3:00 PM | |
| (2) Duke @ Wake Forest | 3:30 PM | ESPN |
| (3) Baylor @ (NFO) Utah | 3:30 PM | |
| (FFO) Clemson @ Virginia Tech | 4:00 PM | ACC Network |
| (11) Ole Miss @ Missouri | 5:00 PM | SEC Network |
(12) Liberty @  FIU | 5:00 PM | ESPN+ |
| (1) Houston @ (1) Kansas | 5:30 PM | |
| (NFO) Notre Dame @ Virginia | 5:30 PM | |
| (2) Connecticut @ (11) Xavier | 7:00 PM | FOX |
| (9) Saint Mary's College @ Washington State | 7:00 PM | |
| (2) Tennessee @ (1) Auburn | 7:30 PM | |
| (10) LSU @ (4) Alabama | 7:30 PM | SEC Network |
| (FFO) Oklahoma @ (9) Arkansas | 7:30 PM | |
| (FFO) Miami (FL) @ California | 7:30 PM | |
| (12) Grand Canyon @ Utah Tech | 8:00 PM | |
| (3) Cincinnati @ (7) BYU | 9:00 PM | ESPN2 |
| San Diego State @ (9) Nevada | 9:00 PM | |
| San Diego @ (NFO) San Francisco | 9:00 PM | |
| Hawaii @ (12) UC Irvine | 9:00 PM | |
| (5) Saint John's @ Georgetown | 5:30 PM | FS1 |
| (3) Kentucky @ (2) Tennessee | 6:00 PM | ESPN |
| UCF @ (1) Kansas | 7:00 PM | ESPN+ |
| Minnesota @ (10) Michigan State | 7:00 PM | Peacock |
| (11) VCU @ Saint Louis | 7:00 PM | |
| (NFO) Dayton @ Saint Bonaventure | 7:00 PM | |
| (4) Marquette @ Butler | 7:30 PM | FS1 |
| (3) Baylor @ (7) BYU | 8:00 PM | |
| (4) North Carolina @ (6) Pittsburgh | 8:00 PM | ESPN |
| (FFO) Oklahoma @ (5) Texas A&M | 8:00 PM | SEC Network |
| Georgia Tech @ (NFO) Notre Dame | 8:00 PM | ACC Network |
| (3) Cincinnati @ (NFO) Utah | 9:00 PM | CBSSN |
| Oregon State @ (1) Gonzaga | 10:00 PM | |
| Georgia @ (4) Alabama | 0:00 | |
 Utah Valley @ (12) Grand Canyon | 0:00 | |
| (6) Florida @ (2) Tennessee | 11:00 AM | |
| Providence @ (5) Saint John's | 11:00 AM | CBSSN |
| (6) Pittsburgh @ Wake Forest | 11:00 AM | |
| (5) Arizona @ Arizona State | 12:00 PM | CBS |
| (5) Creighton @ Villanova | 12:00 PM | FOX |
| Missouri @ (7) Mississippi State | 12:00 PM | SEC Network |
| (FFO) Clemson @ (FFO) North Carolina State | 12:30 PM | |
| Kansas State @ (2) Iowa State | 1:00 PM | |
| (7) Wisconsin @ Northwestern | 1:00 PM | FS1 |
| (NFO) Utah @ Oklahoma State | 2:00 PM | ESPN+ |
| (8) Michigan @ Rutgers | 2:30 PM | FOX |
| Vanderbilt @ (FFO) Oklahoma | 2:30 PM | SEC Network |
| (1) Auburn @ (11) Ole Miss | 3:00 PM | |
| (1) Kansas @ (3) Baylor | 3:00 PM | ESPN |
| (7) BYU @ UCF | 3:00 PM | ESPN+ |
 Richmond @ (11) VCU | 3:00 PM | |
| Fresno State @ (11) Boise State | 3:00 PM | |
| (10) Michigan State @ USC | 3:30 PM | Peacock |
| Brown @ (12) Princeton | 4:00 PM | |
(12) Liberty @  Jacksonville State | 4:00 PM | ESPN+ |
| (3) Texas Tech @ (1) Houston | 5:00 PM | ESPN2 |
| (7) Texas @ (10) LSU | 5:00 PM | SEC Network |
| (4) North Carolina @ (2) Duke | 5:30 PM | ESPN |
| (2) Connecticut @ (4) Marquette | 7:00 PM | FOX |
| (NFO) Notre Dame @ (FFO) Miami (FL) | 7:00 PM | ESPN2 |
| (5) Texas A&M @ South Carolina | 7:30 PM | SEC Network |
| (9) Arkansas @ (3) Kentucky | 8:00 PM | ESPN |
 New Mexico @ (11) Utah State | 8:30 PM | |
| Washington State @ (NFO) San Francisco | 9:00 PM | |
 UC Davis @ (12) UC Irvine | 9:00 PM | |
| (1) Gonzaga @ (9) Saint Mary's College | 10:00 PM | ESPN |
| UNLV @ (9) Nevada | 10:00 PM | |
| Davidson @ (NFO) Dayton | 0:00 | |
| (4) Marquette @ (5) Saint John's | 5:30 PM | FS1 |
| (3) Kentucky @ (11) Ole Miss | 6:00 PM | ESPN |
| (4) Purdue @ (11) Iowa | 6:00 PM | Peacock |
| Vanderbilt @ (6) Florida | 6:00 PM | SEC Network |
| Minnesota @ (10) Penn State | 6:00 PM | BTN |
| La Salle @ (11) VCU | 6:00 PM | |
| (NFO) Notre Dame @ Florida State | 6:00 PM | ACC Network |
| Oklahoma State @ (1) Houston | 7:00 PM | ESPN+ |
| (11) Utah State @ Wyoming | 7:30 PM | |
| Georgetown @ (11) Xavier | 7:30 PM | FS1 |
| (FFO) Oklahoma @ (1) Auburn | 8:00 PM | SEC Network |
| (3) Baylor @ (3) Texas Tech | 8:00 PM | ESPN2 |
| (8) Indiana @ (7) Wisconsin | 8:00 PM | Peacock |
| (9) Nevada @ Air Force | 8:00 PM | |
| Georgia Tech @ (FFO) Clemson | 8:00 PM | ACC Network |
| (10) Michigan State @ (8) UCLA | 9:00 PM | Peacock |
| (5) Arizona @ (7) BYU | 10:00 PM | |
| (11) Boise State @ UNLV | 10:00 PM | |
| (1) Gonzaga @ Pacific | 0:00 | |
| (2) Tennessee @ (FFO) Oklahoma | 11:00 AM | |
| South Carolina @ (3) Kentucky | 11:00 AM | |
| (8) Oregon @ (10) Michigan State | 11:00 AM | FOX |
| TCU @ (2) Iowa State | 12:00 PM | ESPN+ |
| (7) Texas @ Vanderbilt | 12:00 PM | SEC Network |
| (7) Wisconsin @ (11) Iowa | 12:00 PM | NBC |
| (8) Michigan @ (8) Indiana | 12:00 PM | CBS |
| Virginia Tech @ (NFO) Notre Dame | 12:00 PM | |
| (1) Kansas @ Kansas State | 1:00 PM | ESPN |
| UCF @ (3) Baylor | 1:00 PM | ESPN+ |
| (4) Marquette @ (5) Creighton | 1:00 PM | FOX |
| (FFO) Miami (FL) @ Louisville | 1:00 PM | ESPN2 |
| (5) Texas A&M @ Missouri | 2:30 PM | SEC Network |
| (6) Florida @ (1) Auburn | 3:00 PM | |
| (1) Houston @ Colorado | 3:00 PM | ESPN+ |
| (6) Pittsburgh @ (4) North Carolina | 3:00 PM | |
| (10) Penn State @ (8) UCLA | 3:00 PM | BTN |
| (NFO) Utah @ West Virginia | 4:00 PM | ESPN+ |
| (2) Duke @ (FFO) Clemson | 5:00 PM | ESPN |
| (7) BYU @ (3) Cincinnati | 5:00 PM | ESPN2 |
| (6) Illinois @ Minnesota | 5:00 PM | BTN |
| (7) Mississippi State @ Georgia | 5:00 PM | SEC Network |
| (FFO) North Carolina State @ Stanford | 6:00 PM | ACC Network |
| Sam Houston State @ (12) Liberty | 6:00 PM | ESPNU |
| (4) Alabama @ (9) Arkansas | 7:00 PM | ESPN |
| (12) Grand Canyon @ California Baptist | 7:00 PM | |
| (11) Ole Miss @ (10) LSU | 7:30 PM | SEC Network |
| (3) Texas Tech @ (5) Arizona | 9:00 PM | ESPN |
| (9) Saint Mary's College @ Oregon State | 9:00 PM | |
| UC San Diego @ (12) UC Irvine | 9:00 PM | |
| (NFO) San Francisco @ Loyola-Marymount | 10:00 PM | |
| (1) Auburn @ Vanderbilt | 6:00 PM | SEC Network |
| (2) Tennessee @ (3) Kentucky | 6:00 PM | ESPN |
| (2) Iowa State @ UCF | 6:00 PM | ESPN+ |
| (NFO) Utah @ (3) Cincinnati | 6:00 PM | ESPN+ |
| (4) Purdue @ (8) Michigan | 6:00 PM | Peacock |
| (6) Florida @ (7) Mississippi State | 6:00 PM | |
| (7) BYU @ West Virginia | 6:00 PM | CBSSN |
| Syracuse @ (FFO) Miami (FL) | 6:00 PM | ACC Network |
| (5) Arizona @ Kansas State | 7:00 PM | ESPN+ |
| (8) UCLA @ (6) Illinois | 7:00 PM | Peacock |
| DePaul @ (4) Marquette | 7:30 PM | Peacock |
| Colorado @ (1) Kansas | 8:00 PM | |
| (2) Connecticut @ (5) Creighton | 8:00 PM | CBSSN |
| (4) Alabama @ (7) Texas | 8:00 PM | |
| Georgia @ (5) Texas A&M | 8:00 PM | SEC Network |
| (6) Pittsburgh @ SMU | 8:00 PM | ACC Network |
| (8) Indiana @ (10) Michigan State | 8:00 PM | Peacock |
| (10) Penn State @ USC | 8:00 PM | BTN |
| Northwestern @ (8) Oregon | 10:00 PM | BTN |
| Santa Clara @ (9) Saint Mary's College | 10:00 PM | ESPN2 |
| Colorado State @ (11) Utah State | 10:00 PM | |
| Pepperdine @ (1) Gonzaga | 0:00 | |
| (12) Grand Canyon @ UTA | 0:00 | |
| (9) Arkansas @ (5) Texas A&M | 11:00 AM | |
| (FFO) Miami (FL) @ (6) Pittsburgh | 11:00 AM | |
| DePaul @ (11) Xavier | 11:00 AM | FS1 |
| (FFO) Clemson @ Florida State | 11:00 AM | |
| Vanderbilt @ (2) Tennessee | 12:00 PM | SEC Network |
| (7) Wisconsin @ (4) Purdue | 12:00 PM | CBS |
| (1) Houston @ (5) Arizona | 1:00 PM | |
| West Virginia @ (3) Baylor | 1:00 PM | |
| Washington @ (10) Penn State | 1:00 PM | BTN |
| Boston College @ (FFO) North Carolina State | 1:00 PM | ACC Network |
| (2) Connecticut @ Seton Hall | 1:30 PM | FOX |
| Duquesne @ (NFO) Dayton | 1:30 PM | |
| (3) Texas Tech @ Oklahoma State | 2:00 PM | ESPN+ |
| (1) Auburn @ (4) Alabama | 3:00 PM | |
| Stanford @ (2) Duke | 3:00 PM | ABC |
| (3) Cincinnati @ (2) Iowa State | 3:00 PM | |
(12) Princeton @  Yale | 4:00 PM | |
| (4) North Carolina @ Syracuse | 5:00 PM | ESPN |
| (7) Mississippi State @ (11) Ole Miss | 5:00 PM | |
| (10) LSU @ (FFO) Oklahoma | 5:00 PM | SEC Network |
| (3) Kentucky @ (7) Texas | 7:00 PM | ESPN |
| (10) Michigan State @ (6) Illinois | 7:00 PM | FOX |
| South Carolina @ (6) Florida | 7:30 PM | SEC Network |
| Kansas State @ (7) BYU | 8:00 PM | ESPN+ |
(12) Liberty @  UTEP | 8:00 PM | ESPN+ |
| (1) Kansas @ (NFO) Utah | 9:00 PM | ESPN |
| Washington State @ (9) Saint Mary's College | 9:00 PM | |
| (11) Boise State @ San Diego State | 9:00 PM | |
| (NFO) San Francisco @ San Diego | 9:00 PM | |
| (12) UC Irvine @ Hawaii | 10:59 PM | |
| Villanova @ (2) Connecticut | 5:30 PM | FS1 |
| (4) Purdue @ (10) Michigan State | 6:00 PM | Peacock |
| (5) Texas A&M @ (7) Mississippi State | 6:00 PM | SEC Network |
| Syracuse @ (6) Pittsburgh | 6:00 PM | ACC Network |
| (FFO) Oklahoma @ (6) Florida | 6:00 PM | ESPN2 |
| Colorado @ (2) Iowa State | 7:00 PM | ESPN+ |
| (3) Texas Tech @ TCU | 7:00 PM | ESPN+ |
| Butler @ (11) Xavier | 7:00 PM | Peacock |
| (6) Illinois @ (7) Wisconsin | 7:30 PM | FS1 |
| (1) Houston @ Arizona State | 8:00 PM | |
| (1) Kansas @ (7) BYU | 8:00 PM | |
| Seton Hall @ (4) Marquette | 8:00 PM | CBSSN |
| (9) Nevada @ Colorado State | 8:00 PM | |
| South Carolina @ (10) LSU | 8:00 PM | SEC Network |
| Minnesota @ (8) UCLA | 9:30 PM | FS1 |
| Portland @ (9) Saint Mary's College | 0:00 | |
 UMass @ (11) VCU | 5:00 PM | |
| Nebraska @ (10) Penn State | 5:30 PM | BTN |
| (3) Cincinnati @ West Virginia | 6:00 PM | ESPN2 |
| Vanderbilt @ (3) Kentucky | 6:00 PM | SEC Network |
| (FFO) North Carolina State @ (4) North Carolina | 6:00 PM | |
| SMU @ (NFO) Notre Dame | 6:00 PM | ACC Network |
| (8) Oregon @ (11) Iowa | 7:30 PM | BTN |
| (9) Arkansas @ (1) Auburn | 8:00 PM | |
| (1) Gonzaga @ Washington State | 8:00 PM | ESPN2 |
| (4) Alabama @ Missouri | 8:00 PM | SEC Network |
| (5) Saint John's @ DePaul | 8:00 PM | FS1 |
| San Jose State @ (11) Utah State | 8:00 PM | |
| (FFO) Miami (FL) @ Florida State | 8:00 PM | ACC Network |
| New Mexico @ (11) Boise State | 9:00 PM | |
| (9) Saint Mary's College @ (1) Gonzaga | 0:00 | |
| (7) BYU @ (5) Arizona | 0:00 | |
| (2) Tennessee @ (5) Texas A&M | 11:00 AM | |
| TCU @ (3) Cincinnati | 11:00 AM | |
| (8) Oregon @ (7) Wisconsin | 11:00 AM | FOX |
| West Virginia @ (3) Texas Tech | 12:00 PM | ESPN+ |
| (7) Mississippi State @ (FFO) Oklahoma | 12:00 PM | SEC Network |
| (2) Iowa State @ (1) Houston | 1:00 PM | |
| (10) Penn State @ Minnesota | 1:00 PM | BTN |
| Wake Forest @ (FFO) North Carolina State | 1:00 PM | ESPN2 |
| FIU @ (12) Liberty | 1:00 PM | ESPN+ |
| (6) Pittsburgh @ (NFO) Notre Dame | 1:15 PM | |
| (11) Ole Miss @ Vanderbilt | 2:30 PM | SEC Network |
| Georgia @ (1) Auburn | 3:00 PM | |
| Oklahoma State @ (1) Kansas | 3:00 PM | CBS |
| (3) Baylor @ Colorado | 3:00 PM | ESPN+ |
| Virginia @ (4) North Carolina | 3:00 PM | ESPN |
| George Mason @ (11) VCU | 3:00 PM | |
| Washington @ (11) Iowa | 3:00 PM | FS1 |
| (FFO) Clemson @ SMU | 3:00 PM | ACC Network |
| (3) Kentucky @ (4) Alabama | 5:00 PM | ESPN |
| (6) Florida @ (10) LSU | 5:00 PM | SEC Network |
| (11) Boise State @ (9) Nevada | 5:00 PM | |
| Virginia Tech @ (FFO) Miami (FL) | 5:00 PM | ACC Network |
| (2) Duke v. (6) Illinois | 7:00 PM | FOX |
| Missouri @ (9) Arkansas | 7:00 PM | |
| San Diego State @ (11) Utah State | 7:00 PM | |
| Dartmouth @ (12) Princeton | 7:00 PM | |
| California Baptist @ (12) Grand Canyon | 7:00 PM | |
| (7) Texas @ South Carolina | 7:30 PM | SEC Network |
(12) UC Irvine @  Cal State Bakersfield | 8:30 PM | |
(NFO) Dayton @  Rhode Island | 0:00 | |
| Georgetown @ (2) Connecticut | 5:30 PM | FS1 |
| (10) Michigan State @ (10) Maryland | 5:30 PM | BTN |
| (11) Ole Miss @ (1) Auburn | 6:00 PM | |
| Vanderbilt @ (5) Texas A&M | 6:00 PM | SEC Network |
| (FFO) North Carolina State @ Syracuse | 6:00 PM | |
| (NFO) Notre Dame @ (FFO) Clemson | 6:00 PM | ACC Network |
 Rice @ (9) Memphis | 7:00 PM | |
| (10) Penn State @ (8) Indiana | 7:30 PM | BTN |
| (3) Kentucky @ (FFO) Oklahoma | 8:00 PM | SEC Network |
| (NFO) Utah @ (5) Arizona | 8:00 PM | ESPN+ |
| (5) Saint John's @ Butler | 8:00 PM | CBSSN |
| DePaul @ (5) Creighton | 8:00 PM | Peacock |
| (7) Texas @ (9) Arkansas | 8:00 PM | |
| (7) BYU @ Arizona State | 8:30 PM | ESPN+ |
| (6) Ohio State @ USC | 9:30 PM | BTN |
| (11) Utah State @ (11) Boise State | 9:30 PM | |
| (1) Auburn @ (3) Kentucky | 0:00 | |
| (2) Connecticut @ Providence | 11:00 AM | CBS |
| (FFO) Miami (FL) @ (4) North Carolina | 11:00 AM | |
| (10) Maryland @ (10) Penn State | 11:00 AM | BTN |
| (FFO) Clemson @ Virginia | 11:00 AM | |
| (4) Alabama @ (2) Tennessee | 12:00 PM | |
| (9) Arkansas @ South Carolina | 12:00 PM | SEC Network |
| (3) Texas Tech @ (1) Kansas | 1:00 PM | |
| (FFO) Oklahoma @ (11) Ole Miss | 1:00 PM | |
| Richmond @ (NFO) Dayton | 1:00 PM | |
| Seton Hall @ (5) Saint John's | 1:15 PM | CBS |
| (FFO) North Carolina State @ Georgia Tech | 2:00 PM | ACC Network |
| (10) LSU @ (7) Mississippi State | 2:30 PM | SEC Network |
| USC @ (8) Oregon | 3:00 PM | BTN |
| (11) Utah State @ Colorado State | 3:00 PM | |
| (3) Cincinnati @ (1) Houston | 3:30 PM | CBS |
| (5) Creighton @ (11) Xavier | 3:30 PM | FOX |
| (NFO) Notre Dame @ Wake Forest | 4:30 PM | |
| (6) Pittsburgh @ Louisville | 5:00 PM | ESPN2 |
| (8) Indiana @ Washington | 5:00 PM | Peacock |
| Florida State @ (2) Duke | 6:00 PM | ACC Network |
| (11) Boise State @ Fresno State | 6:00 PM | |
| Arizona State @ (NFO) Utah | 6:00 PM | ESPN+ |
| Oklahoma State @ (3) Baylor | 7:00 PM | ESPN+ |
| (4) Marquette @ Georgetown | 7:00 PM | Peacock |
| Georgia @ (7) Texas | 7:00 PM | ESPN2 |
| (5) Texas A&M @ (6) Florida | 7:30 PM | SEC Network |
| (5) Arizona @ (2) Iowa State | 8:00 PM | ESPN |
| West Virginia @ (7) BYU | 9:00 PM | |
| Oregon State @ (9) Saint Mary's College | 9:00 PM | |
 Long Beach State @ (12) UC Irvine | 9:00 PM | |
(12) Grand Canyon @  Seattle University | 9:00 PM | |
| (1) Gonzaga @ (NFO) San Francisco | 10:00 PM | ESPN |
| (1) Auburn @ (5) Texas A&M | 0:00 | |
| (10) LSU @ (3) Kentucky | 0:00 | |
| Saint Louis @ (NFO) Dayton | 0:00 | |
| (4) North Carolina @ Virginia Tech | 6:00 PM | |
| Rutgers @ (4) Purdue | 6:00 PM | Peacock |
| (5) Creighton @ Seton Hall | 6:00 PM | FS1 |
| (9) Memphis @ UTSA | 6:00 PM | |
| (11) VCU @ Duquesne | 6:00 PM | |
| (FFO) Miami (FL) @ Georgia Tech | 6:00 PM | ACC Network |
| (3) Baylor @ TCU | 7:00 PM | ESPN+ |
| (7) Texas @ (7) Mississippi State | 7:00 PM | SEC Network |
| (7) BYU @ (2) Iowa State | 8:00 PM | |
| Nebraska @ (6) Ohio State | 8:00 PM | Peacock |
| (8) Indiana @ (8) Oregon | 8:00 PM | FS1 |
| New Mexico @ (9) Nevada | 8:00 PM | |
| (11) Boise State @ Air Force | 8:00 PM | |
| West Virginia @ (NFO) Utah | 8:00 PM | ESPN+ |
| (9) Arkansas @ Vanderbilt | 9:00 PM | SEC Network |
| Arizona State @ (5) Arizona | 10:00 PM | |
| (10) Maryland @ (8) Michigan | 5:30 PM | BTN |
| Kansas State @ (3) Cincinnati | 6:00 PM | ESPN+ |
| (6) Florida @ (4) Alabama | 6:00 PM | |
| (6) Pittsburgh @ (FFO) North Carolina State | 6:00 PM | ACC Network |
| (11) Xavier @ Butler | 6:00 PM | CBSSN |
| (FFO) Clemson @ Boston College | 6:00 PM | |
| Colorado @ (3) Texas Tech | 7:00 PM | ESPN+ |
| Missouri @ (FFO) Oklahoma | 7:00 PM | SECN+ |
| (4) Marquette @ (2) Connecticut | 7:30 PM | FS1 |
| (7) Wisconsin @ Minnesota | 7:30 PM | BTN |
| (2) Tennessee @ (11) Ole Miss | 8:00 PM | |
| Stanford @ (NFO) Notre Dame | 8:00 PM | |
| Seton Hall @ (2) Connecticut | 0:00 | |
| (5) Saint John's @ (4) Marquette | 0:00 | |
| Butler @ (5) Creighton | 0:00 | |
| USC @ (8) UCLA | 0:00 | FOX |
| Providence @ (11) Xavier | 0:00 | |
| (3) Kentucky @ Missouri | 11:00 AM | |
| (7) Mississippi State @ (9) Arkansas | 11:00 AM | |
| (10) Penn State @ (7) Wisconsin | 12:00 PM | Peacock |
| (2) Iowa State @ Kansas State | 12:30 PM | CBS |
| (4) Alabama @ (1) Auburn | 1:00 PM | ESPN |
| South Carolina @ (2) Tennessee | 1:00 PM | SEC Network |
 Penn @ (12) Princeton | 1:00 PM | |
| (FFO) North Carolina State @ (FFO) Miami (FL) | 1:15 PM | |
| (3) Cincinnati @ Oklahoma State | 2:00 PM | ESPN+ |
| Northwestern @ (10) Maryland | 2:00 PM | Peacock |
(12) Liberty @  Western Kentucky | 2:00 PM | ESPN+ |
| (6) Ohio State @ (8) Indiana | 2:45 PM | CBS |
| (5) Arizona @ (1) Kansas | 3:00 PM | ESPN |
| (5) Texas A&M @ (10) LSU | 3:00 PM | SEC Network |
| Air Force @ (11) Utah State | 3:00 PM | |
| (12) Grand Canyon @ Abilene Christian | 3:00 PM | |
| Boston College @ (6) Pittsburgh | 5:00 PM | ACC Network |
| (11) Ole Miss @ (6) Florida | 5:00 PM | SEC Network |
| Virginia Tech @ (FFO) Clemson | 5:00 PM | ESPNU |
| (2) Duke @ (4) North Carolina | 5:30 PM | ESPN |
| (FFO) Oklahoma @ (7) Texas | 7:00 PM | SEC Network |
| California @ (NFO) Notre Dame | 7:00 PM | ESPNU |
| (1) Houston @ (3) Baylor | 8:00 PM | ESPN2 |
(12) UC Irvine @  UC Santa Barbara | 9:00 PM | |
| (3) Texas Tech @ Arizona State | 9:30 PM | |
| (NFO) Utah @ (7) BYU | 9:30 PM | |
| (9) Nevada @ San Diego State | 9:30 PM | |
Siena @ (11) 
Idaho State @ (8) 
Marshall @ (4) 
Hampton
South Carolina Upstate @ (11) 
Kennesaw State
Northern Colorado @ (3) 
Northwestern State @ (10) 
Delaware State @ (7) 
Chicago State @ (7) 
Charleston Southern @ (FFO) 
Eastern Washington @ (NFO) 
Towson
Buffalo @ (10) 
South Carolina State @ (11) 
Mercyhurst @ (NFO) 
Miami (OH) @ (8) 
Howard @ (3) 
FGCU @ (10) 
Arkansas State @ (9) 
Incarnate Word @ (2) 
Troy @ (1) 
South Dakota State @ (9) 
Eastern Kentucky @ (6) 
Colgate @ (3) 
Omaha @ (2) 
Presbyterian College @ (FFO) 
Arkansas-Pine Bluff @ (7) 
Stephen F. Austin @ (8) 
Nicholls @ (1) 
Toledo @ (1) 
Bradley
North Dakota
Samford @ (5) 
Belmont
Merrimack @ (9) 
Houston Christian @ (5) 
Indiana State @ (6) 
Winthrop @ (8) 
North Texas @ (9) 
Cal State Northridge
Temple
Charlotte
Columbia @ (12) 
Wichita State @ (9) 
UAB @ (9) 
Tulane
Tulsa @ (9)