 Tarleton State @ (2)  Texas | 11:00 AM | SECN+ |
 Central Arkansas @ (NFO)  Oklahoma State | 11:00 AM | ESPN+ |
(1)  South Carolina @  Clemson | 4:00 PM | ESPN2 |
 Long Island @ (10)  Michigan | 4:30 PM | |
 Detroit @ (4)  Michigan State | 5:30 PM | |
(1)  Iowa v. (9)  Kansas | 6:00 PM | BTN |
(16)  Fairleigh Dickinson @ (1)  Connecticut | 6:00 PM | SNY |
(3)  Ohio State @  Ohio | 6:00 PM | ESPN+ |
(7)  Iowa State @  Northern Iowa | 6:00 PM | ESPN+ |
 Albany @ (FFO)  Syracuse | 6:00 PM | ACC Extra |
 Penn @ (NFO)  Villanova | 6:00 PM | |
 Pacific @ (12)  Columbia | 6:00 PM | ESPN+ |
 Milwaukee @ (3)  Kansas State | 6:30 PM | ESPN+ |
 Mercer @ (FFO)  Mississippi State | 6:30 PM | SECN+ |
 Hampton @ (FFO)  Vanderbilt | 6:30 PM | SECN+ |
 Tulane @ (3)  LSU | 7:00 PM | SECN+ |
(8)  Arizona @  Northern Arizona | 7:00 PM | ESPN+ |
(10)  Auburn @  Oregon | 8:00 PM | |
 Grambling State @ (NFO)  California | 9:00 PM | ACC Extra |
 Prairie View A&M @ (9)  Washington | 2:00 PM | |
(5)  Nebraska @ (8)  Creighton | 4:00 PM | |
 Campbell @ (11)  Miami (FL) | 4:00 PM | ACC Extra |
 Lafayette @ (6)  West Virginia | 6:00 PM | ESPN+ |
(NFO)  Florida @ (9)  Florida State | 6:00 PM | ACC Network |
 Samford @ (FFO) Vanderbilt | 6:30 PM | SECN+ |
(10)  Oregon State @ (FFO)  Illinois | 7:00 PM | |
 Saint Joseph's @ (5)  Utah | 8:00 PM | ESPN+ |
| (10) Auburn @ (NFO) California | 8:00 PM | ACC Extra |
(6)  Oklahoma @ (11)  UNLV | 8:30 PM | |
 Morgan State @ (2)  Stanford | 9:00 PM | ACC Extra |
 Bowling Green @ (3) Ohio State | 12:00 PM | |
 Saint Francis (PA) @ (4)  Maryland | 12:00 PM | |
(8)  Louisville v.  South Florida | 12:00 PM | |
 Long Beach State @ (10) Michigan | 1:00 PM | |
(12)  Drake @ (7) Iowa State | 2:00 PM | ESPN+ |
(7)  Gonzaga @  New Mexico | 2:00 PM | |
(FFO) Mississippi State v.  Jacksonville | 2:30 PM | |
(11)  Richmond @  Appalachian State | 2:30 PM | ESPN+ |
(1) South Carolina @ (2)  UCLA | 3:00 PM | FS1 |
(10)  Washington State @ (1) Iowa | 3:00 PM | BTN |
 Idaho State @ (10)  TCU | 4:00 PM | ESPN+ |
 Montana State @ (5) Utah | 8:00 PM | ESPN+ |
(4)  North Carolina State v.  Southern | 10:00 AM | |
| (3) LSU v. (9) Washington | 12:30 PM | |
(7)  Alabama v.  Alabama State | 1:30 PM | |
(3) Kansas State v. (3)  Duke | 2:00 PM | |
(8)  Ole Miss v.  Boston College | 4:00 PM | |
(FFO) Syracuse v.  Missouri | 4:00 PM | |
(6) Oklahoma v.  DePaul | 4:30 PM | |
| (1) Connecticut v. (10) Oregon State | 6:30 PM | |
 Chicago State @ (NFO) Oklahoma State | 6:30 PM | ESPN+ |
(8) Creighton v.  Wichita State | 7:30 PM | |
 Cal Poly @ (2) Stanford | 9:00 PM | ACC Extra |
(3) Ohio State v.  Old Dominion | 10:00 AM | |
(12)  Green Bay v.  Virginia | 11:00 AM | |
(9) Kansas v.  Pittsburgh | 11:30 AM | ESPN+ |
| (NFO) Florida v. Tulane | 12:00 PM | |
| (1) South Carolina v. (7) Iowa State | 12:30 PM | |
(12) Drake v.  Wyoming | 1:30 PM | |
| (10) Auburn v. Northern Iowa | 2:00 PM | ESPN+ |
(11)  Middle Tennessee v.  Purdue | 3:30 PM | |
(10) Washington State v. (14)  Norfolk State | 4:00 PM | |
(7) Gonzaga v.  Missouri State | 4:30 PM | ESPN+ |
(1) Iowa v.  Rhode Island | 5:30 PM | |
| (5) Utah v. (FFO) Mississippi State | 6:30 PM | |
(9) Florida State v.  Texas Tech | 7:00 PM | ESPN+ |
(11) Richmond v.  Oakland | 10:00 AM | |
 Charlotte @ (11) Miami (FL) | 11:00 AM | ACC Extra |
| (12) Drake v. (12) Green Bay | 11:00 AM | |
| (10) Auburn v. Pittsburgh | 11:30 AM | |
(6) West Virginia v. (16)  High Point | 12:30 PM | |
 North Carolina Central @ (9)  North Carolina | 1:00 PM | ACC Extra |
(10) Michigan v.  Belmont | 1:00 PM | |
 New Orleans @ (6)  Baylor | 2:00 PM | ESPN+ |
| (9) Kansas v. Northern Iowa | 2:00 PM | |
(NFO) Florida v. (14)  James Madison | 2:00 PM | |
(3) Ohio State v.  Utah State | 2:30 PM | |
| (10) Washington State v. Virginia | 3:00 PM | |
(4)  Virginia Tech v.  Davidson | 3:30 PM | |
(1)  Notre Dame v. (10) TCU | 4:00 PM | |
 UC San Diego @ (2) Stanford | 4:00 PM | ACC Extra |
| (9) Florida State v. Missouri State | 4:30 PM | |
 East Carolina @ (11) UNLV | 4:30 PM | |
(NFO) Oklahoma State v.  Arkansas | 4:45 PM | |
(2) UCLA v.  Tennessee-Martin | 5:00 PM | |
(2)  USC v.  Saint Louis | 6:00 PM | |
(2) Texas v.  New Mexico State | 6:30 PM | |
| (FFO) Mississippi State v. South Florida | 6:30 PM | |
| (7) Gonzaga v. Texas Tech | 7:00 PM | |
(1) Iowa v.  BYU | 8:00 PM | |
| (1) South Carolina v. Purdue | 10:00 AM | |
| (12) Green Bay v. (14) Norfolk State | 10:00 AM | |
| (7) Iowa State v. (11) Middle Tennessee | 12:30 PM | |
(8) Louisville @ (5)  Colorado | 2:00 PM | ESPN+ |
| Alabama State @ (8) Ole Miss | 2:00 PM | SECN+ |
| (9) Kansas v. (10) Auburn | 2:00 PM | |
| (10) Washington State v. (12) Drake | 2:00 PM | |
(4) Maryland v.  George Mason | 2:30 PM | |
| (1) Notre Dame v. (5) Utah | 4:00 PM | |
(2) UCLA v.  Fresno State | 4:00 PM | |
| (NFO) Oklahoma State v. (11) Richmond | 4:45 PM | |
| (10) TCU v. South Florida | 6:30 PM | |
| (7) Gonzaga v. (9) Florida State | 7:00 PM | |
(8) Creighton @  Xavier | 10:00 AM | |
 San Francisco @ (12) Columbia | 10:00 AM | ESPN+ |
 SIUE @ (11) Middle Tennessee | 11:00 AM | ESPN+ |
(4) Virginia Tech @  Georgia | 4:00 PM | SEC Network |
| (6) Oklahoma @ (8) Louisville | 4:00 PM | ESPN2 |
| (FFO) Vanderbilt @ (11) Miami (FL) | 4:00 PM | ACC Network |
 Georgetown @ (11) Richmond | 5:00 PM | ESPN+ |
(16)  Southern Indiana @ (5)  Indiana | 6:00 PM | |
 IU Indianapolis @ (12) Green Bay | 6:00 PM | ESPN+ |
(9) Florida State @ (7)  Tennessee | 6:15 PM | SEC Network |
(FFO) Syracuse @ (11)  Texas A&M | 6:15 PM | ESPNU |
(FFO) Mississippi State @  Georgia Tech | 6:15 PM | ACC Network |
 FAU @ (10) TCU | 6:30 PM | ESPN+ |
 Houston Christian @ (NFO) Oklahoma State | 6:30 PM | ESPN+ |
 Texas Southern @ (6) Baylor | 7:00 PM | ESPN+ |
(14)  Eastern Washington @ (12)  South Dakota State | 7:00 PM | |
| (10) Washington State @ Oregon | 8:00 PM | |
 Kentucky @ (9) North Carolina | 4:00 PM | ESPN2 |
| (10) Auburn @ Virginia | 5:00 PM | ACC Network |
| (2) Texas @ (1) Notre Dame | 6:00 PM | ESPN |
| (8) Ole Miss @ (4) North Carolina State | 6:00 PM | ESPN2 |
 South Carolina Upstate @ (3) Kansas State | 6:30 PM | ESPN+ |
| Wichita State @ (9) Kansas | 6:30 PM | ESPN+ |
(15)  Grand Canyon @ (8) Arizona | 7:00 PM | ESPN+ |
| (NFO) Florida @ Clemson | 7:00 PM | ACC Network |
| (3) Duke @ (1) South Carolina | 8:00 PM | ESPN |
| (2) Stanford @ (3) LSU | 8:00 PM | ESPN2 |
| Utah State @ (5) Utah | 8:00 PM | ESPN+ |
| (7) Alabama @ (NFO) California | 8:00 PM | ESPNU |
| (10) Oregon State @ Pacific | 8:00 PM | ESPN+ |
(12) South Dakota State @  Montana | 0:00 | ESPN+ |
(5) Indiana @ (6)  Penn State | 12:00 PM | |
| (11) Middle Tennessee @ Belmont | 12:00 PM | ESPN+ |
| (4) Maryland @ Purdue | 1:00 PM | |
(12) Green Bay @  Purdue Fort Wayne | 1:00 PM | ESPN+ |
 Southern Utah @ (5) Colorado | 2:00 PM | ESPN+ |
| (8) Creighton @ Northern Iowa | 2:00 PM | ESPN+ |
| (2) USC @ Oregon | 3:00 PM | BTN |
| (NFO) California @ Pacific | 4:00 PM | ESPN+ |
| (1) Iowa v. (7) Tennessee | 6:00 PM | FOX |
| (1) Connecticut v. (8) Louisville | 8:00 PM | FOX |
| (1) Notre Dame @ (FFO) Syracuse | 11:00 AM | ACC Network |
 Central Michigan @ (7) Iowa State | 12:00 PM | ESPN+ |
| (2) Texas @ (14) James Madison | 1:00 PM | ESPN+ |
| Old Dominion @ (4) North Carolina State | 1:00 PM | ACC Extra |
| DePaul @ (4) Michigan State | 1:00 PM | |
 Minnesota @ (5) Nebraska | 1:00 PM | BTN |
 Tennessee State @ (8) Ole Miss | 1:00 PM | SEC Network |
 Coppin State @ (9) North Carolina | 1:00 PM | ACC Extra |
 SMU @ (9) Florida State | 1:00 PM | ACC Network |
 Northwestern @ (10) Michigan | 1:00 PM | |
 Bethune-Cookman @ (11) Miami (FL) | 1:00 PM | ACC Extra |
(NFO) Villanova @ (14)  Fairfield | 1:00 PM | ESPN+ |
 Marshall @ (NFO) Florida | 1:00 PM | SECN+ |
| (11) Richmond v. (12) Columbia | 1:00 PM | |
| Alabama State @ (6) Oklahoma | 1:30 PM | SECN+ |
| (3) LSU v. Grambling State | 2:00 PM | |
| (11) UNLV @ (6) Baylor | 2:00 PM | ESPN+ |
(7) Gonzaga @  Colorado State | 2:00 PM | |
 UAB @ (10) Auburn | 2:00 PM | SECN+ |
| (FFO) Illinois @ (3) Ohio State | 3:00 PM | BTN |
| (3) Kansas State @ (11) Texas A&M | 3:00 PM | SEC Network |
| (4) Virginia Tech @ (3) Duke | 3:00 PM | ACC Network |
 Princeton @ (5) Utah | 3:00 PM | ESPN+ |
| (2) UCLA @ (9) Washington | 4:00 PM | |
| (FFO) Mississippi State @ Chicago State | 5:00 PM | |
| (1) South Carolina @ (10) TCU | 6:00 PM | ESPN2 |
 Youngstown State @ (3) Ohio State | 10:00 AM | |
| North Carolina Central @ (7) Tennessee | 1:00 PM | SECN+ |
| (8) Creighton @ (12) Green Bay | 1:00 PM | ESPN+ |
| Detroit @ (10) Michigan | 2:00 PM | |
| (FFO) Mississippi State v. Belmont | 2:00 PM | SECN+ |
 Evansville @ (FFO) Vanderbilt | 2:00 PM | SECN+ |
| Northern Iowa @ (12) South Dakota State | 2:00 PM | |
| (2) UCLA @ Long Beach State | 4:00 PM | ESPN+ |
| (14) Eastern Washington @ (7) Gonzaga | 4:00 PM | ESPN+ |
| (3) Kansas State v. (11) Middle Tennessee | 5:00 PM | |
| (5) Utah @ (9) Washington | 8:30 PM | BTN |
| (1) Iowa @ (4) Michigan State | 11:00 AM | BTN |
| (11) Miami (FL) @ Pittsburgh | 11:00 AM | ACC Network |
 Longwood @ (NFO) Florida | 11:00 AM | SEC Network |
| (2) Texas @ (11) Richmond | 12:00 PM | ESPN+ |
| (4) North Carolina State @ (8) Louisville | 12:00 PM | ABC |
(16)  Chattanooga @ (5) Nebraska | 12:00 PM | |
| Georgetown @ (1) Connecticut | 12:30 PM | SNY |
| South Florida @ (1) South Carolina | 1:00 PM | SEC Network |
 Eastern Michigan @ (1) Notre Dame | 1:00 PM | ACC Extra |
(6) West Virginia @ (13)  Temple | 1:00 PM | ESPN2 |
| Georgia Tech @ (9) North Carolina | 1:00 PM | ACC Network |
 Drexel @ (9) Florida State | 1:00 PM | ACC Extra |
| (16) Southern Indiana @ (FFO) Illinois | 1:00 PM | |
| (14) James Madison @ (NFO) Villanova | 1:00 PM | |
 Oral Roberts @ (6) Oklahoma | 1:30 PM | SECN+ |
 Elon @ (2) USC | 2:00 PM | |
 Louisiana @ (3) LSU | 2:00 PM | SECN+ |
| (6) Penn State @ (9) Kansas | 2:00 PM | ESPNU |
 Murray State @ (7) Alabama | 2:00 PM | SECN+ |
 South Alabama @ (8) Ole Miss | 2:00 PM | SECN+ |
 Louisiana Tech @ (10) TCU | 2:00 PM | ESPN+ |
| (11) UNLV @ DePaul | 2:00 PM | |
 Radford @ (4) Virginia Tech | 3:00 PM | ACC Extra |
(16)  UC Irvine @ (10) Oregon State | 3:00 PM | ESPN+ |
 Austin Peay @ (NFO) California | 4:00 PM | ACC Extra |
 Eastern Illinois @ (7) Iowa State | 5:00 PM | ESPN+ |
 Bellarmine @ (5) Indiana | 6:00 PM | |
 William & Mary @ (4) Maryland | 10:00 AM | |
| (4) Michigan State v. Montana | 11:00 AM | |
(11) Miami (FL) v.  Nevada | 12:30 AM | |
 Mississippi Valley State @ (11) Texas A&M | 1:00 PM | SECN+ |
 Furman @ (9) Washington | 4:00 PM | |
| Jacksonville @ (9) Florida State | 5:00 PM | ACC Extra |
 Charleston Southern @ (1) South Carolina | 6:00 PM | SECN+ |
| (14) James Madison @ (4) North Carolina State | 6:00 PM | ACC Extra |
(FFO) Vanderbilt @  Dayton | 6:00 PM | ESPN+ |
(3) LSU @  UIC | 7:00 PM | ESPN+ |
| (7) Gonzaga @ San Francisco | 8:00 PM | ESPN+ |
(10) Washington State @  San Diego | 8:00 PM | ESPN+ |
(10) Oregon State v.  Western Kentucky | 10:00 PM | |
(7) Tennessee v.  Tulsa | 10:00 AM | |
 Dartmouth @ (FFO) Syracuse | 10:00 AM | ACC Extra |
| Campbell @ (4) Virginia Tech | 11:00 AM | |
| (14) Norfolk State @ (9) North Carolina | 11:00 AM | ACC Extra |
 West Georgia @ (FFO) Vanderbilt | 11:00 AM | SECN+ |
(12) Columbia @  Wagner | 11:00 AM | |
| (3) Duke @ South Florida | 12:00 PM | ESPNU |
| Mississippi Valley State @ (8) Ole Miss | 12:00 PM | SECN+ |
| Alabama State @ (10) Auburn | 12:00 PM | SECN+ |
| (7) Alabama v. (11) Richmond | 12:15 PM | |
| (5) Nebraska @ Georgia Tech | 1:00 PM | ACC Extra |
(10) TCU @  UCF | 1:00 PM | ESPN+ |
 Saint John's @ (NFO) Villanova | 1:00 PM | |
(12) Drake @  Saint Thomas | 1:00 PM | |
 North Florida @ (NFO) Florida | 1:45 PM | SECN+ |
| (6) Baylor @ (9) Kansas | 4:00 PM | ESPN+ |
| (7) Iowa State @ (NFO) Oklahoma State | 4:00 PM | ESPN2 |
| (7) Gonzaga @ San Diego | 4:00 PM | ESPN+ |
(8) Louisville @  Memphis | 4:00 PM | ESPNU |
 UC Riverside @ (11) UNLV | 4:30 PM | |
 Arizona State @ (5) Utah | 5:00 PM | ESPN+ |
| (8) Arizona @ BYU | 5:00 PM | ESPN+ |
| (2) USC @ (1) Connecticut | 7:00 PM | FOX |
| (6) West Virginia @ (5) Colorado | 7:00 PM | ESPN+ |
 Fordham @ (NFO) California | 7:00 PM | |
| Alabama State @ (NFO) Florida | 2:45 AM | SECN+ |
| Virginia @ (1) Notre Dame | 11:00 AM | ACC Network |
| Jacksonville @ (7) Alabama | 11:00 AM | SECN+ |
 Alabama A&M @ (FFO) Vanderbilt | 11:00 AM | SEC Network |
| (4) Michigan State @ (4) Maryland | 12:00 PM | |
(12) Columbia @  Towson | 12:00 PM | |
| (12) Drake @ Evansville | 12:00 PM | ESPN+ |
 Providence @ (1) Connecticut | 12:30 PM | SNY |
 Wofford @ (1) South Carolina | 1:00 PM | SEC Network |
(3) Ohio State @  Rutgers | 1:00 PM | |
| Albany @ (3) LSU | 1:00 PM | SECN+ |
| (8) Louisville @ Boston College | 1:00 PM | ACC Network |
| (11) Middle Tennessee @ Princeton | 1:00 PM | |
| Dayton @ (11) Richmond | 1:00 PM | ESPN+ |
| Purdue @ (1) Iowa | 2:00 PM | |
 Brown @ (10) TCU | 2:00 PM | ESPN+ |
| (14) Norfolk State @ (10) Auburn | 2:00 PM | SECN+ |
 South Carolina State @ (FFO) Mississippi State | 2:00 PM | SECN+ |
 UTRGV @ (2) Texas | 3:00 PM | SEC Network |
| (9) North Carolina @ (11) Miami (FL) | 3:00 PM | ACC Network |
| (5) Nebraska @ (2) UCLA | 4:00 PM | |
| New Mexico State @ (6) Oklahoma | 4:00 PM | SECN+ |
| Fresno State @ (11) UNLV | 4:00 PM | |
| Clemson @ (4) North Carolina State | 5:00 PM | ACC Network |
 Winthrop @ (7) Tennessee | 5:30 PM | SECN+ |
| (10) Michigan @ (2) USC | 9:00 PM | BTN |
| (9) Florida State @ (4) Virginia Tech | 5:00 PM | ACC Network |
 Loyola-Marymount @ (10) Oregon State | 5:00 PM | |
| (11) Richmond @ Fordham | 5:30 PM | |
| (1) South Carolina @ Missouri | 6:00 PM | SEC Network |
| (3) Duke @ Boston College | 6:00 PM | |
| Rutgers @ (4) Maryland | 6:00 PM | |
| (NFO) Florida @ (7) Alabama | 6:00 PM | |
| (8) Ole Miss @ (10) Auburn | 6:00 PM | |
| (11) Miami (FL) @ (8) Louisville | 6:00 PM | |
| (FFO) Mississippi State @ Kentucky | 6:00 PM | |
| (FFO) Syracuse @ Georgia Tech | 6:00 PM | |
| (NFO) California @ Clemson | 6:00 PM | |
| UIC @ (12) Drake | 6:00 PM | |
 Northern Kentucky @ (12) Green Bay | 6:00 PM | |
| Georgia @ (FFO) Vanderbilt | 6:30 PM | |
 FIU @ (11) Middle Tennessee | 6:30 PM | ESPN+ |
| (2) Stanford @ SMU | 7:00 PM | ACC Network |
| (7) Tennessee @ (11) Texas A&M | 7:00 PM | |
| (12) South Dakota State @ Oral Roberts | 7:00 PM | |
| (2) Texas @ (6) Oklahoma | 8:00 PM | ESPN2 |
| (3) LSU @ Arkansas | 8:00 PM | SEC Network |
(7) Gonzaga @  Portland | 8:00 PM | |
 Santa Clara @ (10) Washington State | 8:00 PM | |
| (2) UCLA @ (5) Indiana | 11:00 AM | FOX |
| (8) Creighton @ Providence | 1:00 PM | |
| (8) Arizona @ UCF | 1:00 PM | |
| (12) Columbia @ Penn | 1:00 PM | |
 Wright State @ (12) Green Bay | 1:00 PM | |
| (5) Colorado @ (6) Baylor | 2:00 PM | |
| (9) Kansas @ (NFO) Oklahoma State | 2:00 PM | |
| (10) Oregon State @ (10) Washington State | 2:00 PM | |
(12) South Dakota State @  Denver | 2:00 PM | |
 Valparaiso @ (12) Drake | 2:00 PM | |
 Liberty @ (11) Middle Tennessee | 3:00 PM | ESPNU |
| Texas Tech @ (3) Kansas State | 4:00 PM | |
| Santa Clara @ (7) Gonzaga | 4:00 PM | |
| BYU @ (6) West Virginia | 5:00 PM | |
 Cincinnati @ (10) TCU | 7:00 PM | |
(11) UNLV @  Boise State | 7:00 PM | |
| Pittsburgh @ (3) Duke | 11:00 AM | ACC Network |
| (4) Virginia Tech @ (11) Miami (FL) | 11:00 AM | |
| Georgia @ (NFO) Florida | 11:00 AM | SEC Network |
| (1) Notre Dame @ (9) North Carolina | 12:00 PM | ESPN |
| Northwestern @ (3) Ohio State | 12:00 PM | |
(11) Richmond @  UMass | 12:00 PM | |
| (1) Connecticut @ (NFO) Villanova | 12:30 PM | SNY |
| (1) South Carolina @ (FFO) Mississippi State | 1:00 PM | SEC Network |
| (2) Stanford @ Clemson | 1:00 PM | |
| Boston College @ (4) North Carolina State | 1:00 PM | |
(8) Louisville @  Wake Forest | 1:00 PM | ACC Network |
| (FFO) Syracuse @ (9) Florida State | 1:00 PM | ACC Network |
| Arkansas @ (2) Texas | 2:00 PM | |
| (6) Penn State @ (5) Nebraska | 2:00 PM | |
| (6) Oklahoma @ (7) Tennessee | 2:00 PM | ESPN |
| Missouri @ (7) Alabama | 2:00 PM | |
| (8) Ole Miss @ (11) Texas A&M | 2:00 PM | |
| Kentucky @ (FFO) Vanderbilt | 2:00 PM | |
| (FFO) Illinois @ Minnesota | 2:00 PM | |
| (10) Auburn @ (3) LSU | 3:00 PM | SEC Network |
| (5) Utah @ (7) Iowa State | 4:00 PM | ESPN2 |
| (4) Maryland @ (1) Iowa | 5:00 PM | BTN |
| (NFO) California @ SMU | 5:00 PM | ACC Network |
| (2) USC @ Rutgers | 7:00 PM | BTN |
| George Mason @ (11) Richmond | 5:00 PM | |
| (NFO) Oklahoma State @ Cincinnati | 5:30 PM | |
| (3) Ohio State @ (10) Michigan | 6:00 PM | |
| (6) West Virginia @ Texas Tech | 6:00 PM | |
 Marquette @ (8) Creighton | 6:00 PM | |
| (NFO) Villanova @ Georgetown | 6:00 PM | |
| Xavier @ (1) Connecticut | 6:30 PM | SNY |
| (4) Michigan State @ (5) Nebraska | 7:00 PM | |
| (5) Indiana @ Northwestern | 7:00 PM | |
| (6) Baylor @ (8) Arizona | 7:00 PM | |
| (2) USC @ (4) Maryland | 7:30 PM | FS1 |
| (7) Iowa State @ Arizona State | 7:30 PM | |
| (3) Kansas State @ (5) Utah | 8:00 PM | |
| UCF @ (5) Colorado | 8:00 PM | |
| Colorado State @ (11) UNLV | 8:30 PM | |
| SMU @ (FFO) Syracuse | 9:30 AM | |
| (11) Texas A&M @ (1) South Carolina | 4:00 PM | ESPN2 |
| Kentucky @ (NFO) Florida | 4:00 PM | SEC Network |
| Oregon @ (6) Penn State | 5:00 PM | |
| (8) Louisville @ Pittsburgh | 5:00 PM | |
| (3) LSU @ (7) Tennessee | 5:30 PM | |
| (12) Green Bay @ Youngstown State | 5:30 PM | |
| (1) Iowa @ (FFO) Illinois | 6:00 PM | |
| Wake Forest @ (1) Notre Dame | 6:00 PM | |
| (3) Duke @ (9) North Carolina | 6:00 PM | |
| (4) Virginia Tech @ Georgia Tech | 6:00 PM | |
| Arkansas @ (10) Auburn | 6:00 PM | |
(11) Middle Tennessee @  Kennesaw State | 6:00 PM | ESPN+ |
| (6) Oklahoma @ (FFO) Mississippi State | 6:30 PM | |
| (FFO) Vanderbilt @ (8) Ole Miss | 6:30 PM | |
| (7) Alabama @ (2) Texas | 7:00 PM | |
 Omaha @ (12) South Dakota State | 7:00 PM | |
| San Francisco @ (10) Oregon State | 8:00 PM | |
(10) Washington State @  Saint Mary's College | 8:30 PM | |
| (9) Florida State @ (2) Stanford | 9:00 PM | |
| (4) North Carolina State @ (NFO) California | 9:00 PM | |
(8) Creighton @  Seton Hall | 11:00 AM | |
(12) Columbia @  Cornell | 12:00 PM | |
| (10) Michigan @ Purdue | 1:00 PM | |
(12) Green Bay @  Robert Morris | 1:00 PM | |
(4) Maryland @  Wisconsin | 1:30 PM | BTN |
| (9) Kansas @ (5) Colorado | 2:00 PM | |
| (6) West Virginia @ (NFO) Oklahoma State | 2:00 PM | |
| (7) Gonzaga @ (10) Washington State | 2:00 PM | |
| (NFO) Villanova @ Marquette | 2:00 PM | |
 UMKC @ (12) South Dakota State | 2:00 PM | |
 Houston @ (5) Utah | 2:30 PM | |
(11) Middle Tennessee @  Jacksonville State | 2:30 PM | ESPN+ |
| (1) Connecticut @ Georgetown | 3:00 PM | SNY |
| (7) Iowa State @ (8) Arizona | 3:00 PM | |
| (6) Baylor @ Arizona State | 4:30 PM | |
| (3) Kansas State @ BYU | 5:00 PM | |
| (10) TCU @ Texas Tech | 6:00 PM | |
| (3) Duke @ Virginia | 11:00 AM | ACC Network |
| (2) Texas @ (1) South Carolina | 12:00 PM | ESPN |
| Oregon @ (3) Ohio State | 12:00 PM | |
| (7) Tennessee @ Arkansas | 12:00 PM | SEC Network |
| (1) Notre Dame @ Clemson | 1:00 PM | |
| (9) Washington @ (4) Michigan State | 1:00 PM | |
| Wake Forest @ (4) Virginia Tech | 1:00 PM | |
| (5) Nebraska @ Rutgers | 1:00 PM | |
| Boston College @ (9) North Carolina | 1:00 PM | ACC Network |
| (FFO) Mississippi State @ Georgia | 1:00 PM | |
| (5) Indiana @ (1) Iowa | 2:00 PM | Peacock |
| (4) North Carolina State @ (2) Stanford | 2:00 PM | ESPN |
| (10) Auburn @ Kentucky | 2:00 PM | SEC Network |
| (NFO) Florida @ Missouri | 2:00 PM | |
(12) Drake @  Illinois State | 2:00 PM | |
| (7) Alabama @ (8) Ole Miss | 3:00 PM | |
| Georgia Tech @ (8) Louisville | 3:00 PM | ACC Network |
| (11) UNLV @ New Mexico | 3:00 PM | CBSSN |
| Northwestern @ (2) UCLA | 4:00 PM | |
| (11) Texas A&M @ (6) Oklahoma | 4:00 PM | SEC Network |
| (9) Florida State @ (NFO) California | 4:00 PM | |
| (11) Miami (FL) @ (FFO) Syracuse | 5:00 PM | ACC Network |
| (11) Richmond @ Davidson | 6:00 PM | |
| (6) Penn State @ (2) USC | 7:00 PM | BTN |
| Georgia Tech @ (1) Notre Dame | 5:00 PM | ACC Network |
| (2) Stanford @ Wake Forest | 5:00 PM | |
| Virginia @ (4) Virginia Tech | 5:00 PM | |
| Clemson @ (9) Florida State | 5:00 PM | |
| (1) South Carolina @ (7) Alabama | 6:00 PM | |
| (5) Nebraska @ (1) Iowa | 6:00 PM | BTN |
| (2) Texas @ (10) Auburn | 6:00 PM | |
| Pittsburgh @ (4) North Carolina State | 6:00 PM | |
| (FFO) Illinois @ (5) Indiana | 6:00 PM | Peacock |
| Missouri @ (6) Oklahoma | 6:00 PM | |
| (FFO) Mississippi State @ (7) Tennessee | 6:00 PM | SEC Network |
| (FFO) Syracuse @ (8) Louisville | 6:00 PM | |
| Boston College @ (11) Miami (FL) | 6:00 PM | |
| Belmont @ (12) Drake | 6:00 PM | |
| Detroit @ (12) Green Bay | 6:00 PM | |
| (8) Arizona @ (3) Kansas State | 6:30 PM | |
| Arizona State @ (9) Kansas | 6:30 PM | |
| (NFO) California @ (3) Duke | 7:00 PM | ACC Network |
| (9) North Carolina @ SMU | 7:00 PM | |
| Georgia @ (11) Texas A&M | 7:00 PM | |
| (3) Ohio State @ Wisconsin | 8:00 PM | Peacock |
| Portland @ (7) Gonzaga | 8:00 PM | |
| (NFO) Florida @ (8) Ole Miss | 8:00 PM | SEC Network |
| (10) Oregon State @ Santa Clara | 8:00 PM | |
| (10) Washington State @ San Francisco | 8:00 PM | |
| Portland @ (10) Oregon State | 0:00 | |
| Rutgers @ (10) Michigan | 11:00 AM | BTN |
| (NFO) Villanova @ Saint John's | 1:00 PM | |
(12) Columbia @  Yale | 1:00 PM | |
| Oakland @ (12) Green Bay | 1:00 PM | |
| DePaul @ (8) Creighton | 2:00 PM | |
| (11) Middle Tennessee @ Western Kentucky | 2:00 PM | ESPN+ |
 North Dakota @ (12) South Dakota State | 2:00 PM | |
| Murray State @ (12) Drake | 2:00 PM | |
| (NFO) Oklahoma State @ UCF | 3:00 PM | |
| (7) Gonzaga @ Loyola-Marymount | 4:00 PM | |
| Purdue @ (9) Washington | 4:00 PM | |
| (10) Washington State @ Santa Clara | 4:00 PM | |
| (5) Colorado @ Cincinnati | 5:00 PM | |
| (2) Stanford @ (3) Duke | 0:00 | |
| (2) USC @ (5) Indiana | 0:00 | NBC |
| (FFO) Syracuse @ Boston College | 11:00 AM | ACC Network |
| Seton Hall @ (1) Connecticut | 12:00 PM | SNY |
| (3) Ohio State @ (6) Penn State | 12:00 PM | |
| (3) LSU @ (NFO) Florida | 12:00 PM | SEC Network |
| (7) Iowa State @ (6) West Virginia | 12:00 PM | |
| Arizona State @ (3) Kansas State | 1:00 PM | |
| Virginia @ (4) North Carolina State | 1:00 PM | |
| (9) North Carolina @ Pittsburgh | 1:00 PM | ACC Network |
| (11) Miami (FL) @ (9) Florida State | 1:00 PM | |
| (NFO) California @ Wake Forest | 1:00 PM | |
 VCU @ (11) Richmond | 1:00 PM | |
| (6) Oklahoma @ (1) South Carolina | 2:00 PM | |
| (4) Michigan State @ (FFO) Illinois | 2:00 PM | |
| (7) Tennessee @ (FFO) Vanderbilt | 2:00 PM | |
| (8) Ole Miss @ (FFO) Mississippi State | 2:00 PM | SEC Network |
| (8) Arizona @ (9) Kansas | 2:00 PM | |
| Missouri @ (10) Auburn | 2:00 PM | |
| (8) Louisville @ (4) Virginia Tech | 3:00 PM | ACC Network |
| Wyoming @ (11) UNLV | 3:00 PM | CBSSN |
| (1) Iowa @ Oregon | 4:00 PM | |
| (7) Alabama @ Arkansas | 4:00 PM | SEC Network |
| SMU @ (1) Notre Dame | 5:00 PM | ACC Network |
| (4) Maryland @ (3) Ohio State | 5:00 PM | BTN |
| (4) North Carolina State @ (FFO) Syracuse | 5:00 PM | ACC Network |
| (4) Virginia Tech @ Pittsburgh | 5:00 PM | |
| (1) Notre Dame @ Boston College | 6:00 PM | |
| (2) UCLA @ Rutgers | 6:00 PM | FS1 |
| Wake Forest @ (9) North Carolina | 6:00 PM | |
| (11) Miami (FL) @ Clemson | 6:00 PM | |
| Kentucky @ (11) Texas A&M | 6:00 PM | SEC Network |
(11) Richmond @  Loyola-Chicago | 6:00 PM | |
| (12) Green Bay @ Wright State | 6:00 PM | |
| (10) Auburn @ (FFO) Mississippi State | 6:30 PM | |
| Arkansas @ (FFO) Vanderbilt | 6:30 PM | |
 Sam Houston State @ (11) Middle Tennessee | 6:30 PM | ESPN+ |
| (3) LSU @ (1) South Carolina | 7:00 PM | ESPN |
| (3) Duke @ SMU | 7:00 PM | ACC Network |
| (FFO) Illinois @ Northwestern | 7:00 PM | BTN |
| (7) Tennessee @ (2) Texas | 8:00 PM | SEC Network |
| (10) Oregon State @ San Francisco | 8:00 PM | |
| Portland @ (10) Washington State | 8:00 PM | |
| (NFO) California @ (2) Stanford | 9:00 PM | |
| (4) Michigan State @ (10) Michigan | 11:00 AM | BTN |
| Louisiana Tech @ (11) Middle Tennessee | 12:00 PM | ESPN+ |
| (12) Green Bay @ Northern Kentucky | 12:00 PM | |
| Xavier @ (NFO) Villanova | 1:00 PM | |
| Penn @ (12) Columbia | 1:00 PM | |
(12) South Dakota State @  South Dakota | 1:00 PM | |
| (3) Kansas State @ (5) Colorado | 2:00 PM | |
| (9) Kansas @ Houston | 2:00 PM | |
| (NFO) Oklahoma State @ Texas Tech | 2:00 PM | |
(7) Gonzaga @  Pepperdine | 3:00 PM | |
(11) UNLV @  San Diego State | 3:00 PM | |
| (5) Utah @ BYU | 3:30 PM | ESPNU |
| UCF @ (7) Iowa State | 4:00 PM | |
| (10) Washington State @ Loyola-Marymount | 4:00 PM | |
| (1) Connecticut @ (8) Creighton | 4:30 PM | FOX |
| (12) Drake @ Missouri State | 6:30 PM | |
| (6) West Virginia @ (8) Arizona | 7:30 PM | |
| (10) Oregon State @ Pacific | 8:00 PM | |
| Pepperdine @ (10) Oregon State | 0:00 | |
| (1) Notre Dame @ (4) Virginia Tech | 5:00 PM | |
| (4) North Carolina State @ Wake Forest | 5:00 PM | |
| Oregon @ (4) Michigan State | 5:00 PM | BTN |
| (8) Ole Miss @ Georgia | 5:00 PM | |
| (9) Florida State @ Boston College | 5:00 PM | ACC Network |
| (6) Oklahoma @ (3) LSU | 6:00 PM | ESPN2 |
| (5) Nebraska @ Purdue | 6:00 PM | |
| (7) Alabama @ Kentucky | 6:00 PM | SEC Network |
| Virginia @ (11) Miami (FL) | 6:00 PM | |
| (FFO) Vanderbilt @ (NFO) Florida | 6:00 PM | |
| (FFO) Illinois @ Rutgers | 6:00 PM | |
 Cleveland State @ (12) Green Bay | 6:00 PM | |
| (11) Texas A&M @ Arkansas | 6:30 PM | |
| (8) Louisville @ SMU | 7:00 PM | ACC Network |
| (11) Middle Tennessee @ New Mexico State | 7:00 PM | ESPN+ |
| (7) Iowa State @ (3) Kansas State | 7:30 PM | ESPN |
| Missouri @ (2) Texas | 8:00 PM | SEC Network |
| San Diego @ (7) Gonzaga | 8:00 PM | |
| Pacific @ (10) Washington State | 8:00 PM | |
| Pittsburgh @ (2) Stanford | 9:00 PM | |
| Minnesota @ (2) USC | 9:00 PM | Peacock |
| (9) North Carolina @ (NFO) California | 9:00 PM | |
| (10) Auburn @ (1) South Carolina | 11:00 AM | SEC Network |
| (1) Notre Dame @ (8) Louisville | 11:00 AM | ESPN2 |
| (5) Nebraska @ (5) Indiana | 11:00 AM | FS1 |
| Oregon @ (10) Michigan | 11:00 AM | |
| Virginia @ (FFO) Syracuse | 11:00 AM | ACC Network |
 Butler @ (1) Connecticut | 12:00 PM | SNY |
| (FFO) Illinois @ (4) Maryland | 12:00 PM | |
| (2) USC @ (1) Iowa | 12:30 PM | FOX |
| (FFO) Mississippi State @ (3) LSU | 1:00 PM | SEC Network |
| SMU @ (4) Virginia Tech | 1:00 PM | |
| Providence @ (8) Creighton | 1:00 PM | FS1 |
| Georgia Tech @ (11) Miami (FL) | 1:00 PM | ACC Network |
| Marquette @ (NFO) Villanova | 1:00 PM | |
| Rhode Island @ (11) Richmond | 1:00 PM | |
| (12) Green Bay @ IU Indianapolis | 1:00 PM | |
| Minnesota @ (2) UCLA | 2:00 PM | BTN |
| (9) North Carolina @ (2) Stanford | 2:00 PM | |
| (3) Kansas State @ (9) Kansas | 2:00 PM | |
| (4) Michigan State @ Northwestern | 2:00 PM | |
| Cincinnati @ (6) Baylor | 2:00 PM | |
| Georgia @ (7) Alabama | 2:00 PM | |
| (7) Tennessee @ Missouri | 2:00 PM | |
| (8) Ole Miss @ (FFO) Vanderbilt | 2:00 PM | |
| Texas Tech @ (5) Colorado | 3:00 PM | ESPNU |
| Kentucky @ (6) Oklahoma | 3:00 PM | SEC Network |
| (10) TCU @ (7) Iowa State | 3:00 PM | FS1 |
| (9) Washington @ (3) Ohio State | 4:00 PM | BTN |
| Pittsburgh @ (NFO) California | 4:00 PM | |
| (2) Texas @ (11) Texas A&M | 5:00 PM | SEC Network |
| Wake Forest @ (9) Florida State | 5:00 PM | ACC Network |
| (1) South Carolina @ Georgia | 5:00 PM | |
| (FFO) Syracuse @ (4) Virginia Tech | 5:00 PM | ACC Network |
| Rutgers @ (5) Indiana | 5:00 PM | BTN |
| (1) Connecticut @ (7) Tennessee | 5:30 PM | ESPN |
| Clemson @ (3) Duke | 6:00 PM | |
| (7) Alabama @ (NFO) Florida | 6:00 PM | SEC Network |
| (9) Florida State @ Virginia | 6:00 PM | |
| (11) Texas A&M @ (10) Auburn | 6:00 PM | |
| Northwestern @ (FFO) Illinois | 6:00 PM | |
| Youngstown State @ (12) Green Bay | 6:00 PM | |
| (3) LSU @ Missouri | 6:30 PM | |
| (6) Oklahoma @ (8) Ole Miss | 6:30 PM | |
| Arkansas @ (FFO) Mississippi State | 6:30 PM | |
| Jacksonville State @ (11) Middle Tennessee | 6:30 PM | ESPN+ |
| (1) Iowa @ Minnesota | 7:00 PM | BTN |
| (10) Michigan @ (5) Nebraska | 7:00 PM | Peacock |
| (NFO) California @ (8) Louisville | 7:00 PM | ACC Network |
| (2) Stanford @ (1) Notre Dame | 7:30 PM | ESPN |
| (FFO) Vanderbilt @ (2) Texas | 8:00 PM | SEC Network |
| (4) Maryland @ Oregon | 8:00 PM | FS1 |
| (10) Oregon State @ Loyola-Marymount | 8:00 PM | |
| (7) Gonzaga @ Saint Mary's College | 8:30 PM | |
| (9) Kansas @ Cincinnati | 11:00 AM | |
| Oral Roberts @ (12) South Dakota State | 11:00 AM | |
| (8) Creighton @ (NFO) Villanova | 1:00 PM | |
| (12) Columbia @ Brown | 1:00 PM | |
| Robert Morris @ (12) Green Bay | 1:00 PM | |
| (3) Kansas State @ (NFO) Oklahoma State | 2:00 PM | |
| (6) West Virginia @ Houston | 2:00 PM | |
| UCF @ (5) Utah | 2:30 PM | |
| Arizona State @ (8) Arizona | 3:00 PM | |
| (10) Washington State @ (7) Gonzaga | 4:00 PM | |
| Texas Tech @ (10) TCU | 4:00 PM | |
| (10) Oregon State @ San Diego | 4:00 PM | |
| New Mexico @ (11) UNLV | 4:00 PM | |
| (5) Colorado @ (7) Iowa State | 5:00 PM | |
| Kennesaw State @ (11) Middle Tennessee | 5:00 PM | ESPN+ |
| BYU @ (6) Baylor | 7:00 PM | |
| (3) Ohio State @ (2) USC | 8:00 PM | FOX |
| (1) Connecticut @ Providence | 11:00 AM | CBSSN |
| (2) Stanford @ (8) Louisville | 11:00 AM | ESPN2 |
| (4) Virginia Tech @ Virginia | 11:00 AM | ACC Network |
| (1) South Carolina @ (2) Texas | 1:00 PM | ESPN |
| (NFO) California @ (1) Notre Dame | 1:00 PM | ACC Network |
| (11) Miami (FL) @ (3) Duke | 1:00 PM | |
| (4) North Carolina State @ (9) Florida State | 1:00 PM | |
| (10) Michigan @ (4) Michigan State | 1:00 PM | FS1 |
| (6) Penn State @ Northwestern | 1:00 PM | |
| (7) Alabama @ (FFO) Mississippi State | 1:00 PM | SEC Network |
| (9) North Carolina @ Clemson | 1:00 PM | |
| Wake Forest @ (FFO) Syracuse | 1:00 PM | |
(11) Richmond @  Duquesne | 1:00 PM | |
| (5) Indiana @ Minnesota | 2:00 PM | |
 Bradley @ (12) Drake | 2:00 PM | |
| (2) UCLA @ Oregon | 3:00 PM | |
| (7) Tennessee @ (3) LSU | 3:00 PM | ESPN |
| (4) Maryland @ (9) Washington | 3:00 PM | |
| Missouri @ (11) Texas A&M | 3:00 PM | SEC Network |
| (FFO) Illinois @ Wisconsin | 3:00 PM | |
| (7) Gonzaga @ (10) Oregon State | 0:00 | |
| (3) Duke @ Wake Forest | 5:00 PM | |
| (11) Miami (FL) @ (4) North Carolina State | 5:00 PM | ACC Network |
| (8) Louisville @ (9) Florida State | 5:00 PM | |
| (5) Nebraska @ (4) Maryland | 5:30 PM | BTN |
| (10) Auburn @ (7) Tennessee | 5:30 PM | |
| (NFO) Florida @ (1) South Carolina | 6:00 PM | SEC Network |
| (2) Texas @ Kentucky | 6:00 PM | ESPN2 |
| (4) Virginia Tech @ (9) North Carolina | 6:00 PM | |
| (6) Penn State @ (FFO) Illinois | 6:00 PM | |
| (12) Drake @ Murray State | 6:00 PM | |
| (12) Green Bay @ Oakland | 6:00 PM | |
| Rutgers @ (1) Iowa | 6:30 PM | |
| Minnesota @ (3) Ohio State | 6:30 PM | Peacock |
| (8) Ole Miss @ Arkansas | 6:30 PM | |
| (1) Notre Dame @ Pittsburgh | 7:00 PM | ACC Network |
| Saint Joseph's @ (11) Richmond | 7:00 PM | |
| Loyola-Marymount @ (10) Washington State | 8:00 PM | |
| (FFO) Mississippi State @ (FFO) Vanderbilt | 8:00 PM | SEC Network |
| (2) UCLA @ (2) USC | 9:00 PM | Peacock |
| (FFO) Syracuse @ (2) Stanford | 9:00 PM | ACC Network |
| Boston College @ (NFO) California | 9:00 PM | |
| (8) Ole Miss @ (7) Tennessee | 11:00 AM | SEC Network |
 Harvard @ (12) Columbia | 11:00 AM | ESPNU |
| (1) Connecticut @ (1) South Carolina | 12:00 PM | ABC |
| Wisconsin @ (6) Penn State | 12:00 PM | |
| (4) North Carolina State @ (9) North Carolina | 1:00 PM | ESPN |
| (6) Oklahoma @ Missouri | 1:00 PM | SEC Network |
| (9) Florida State @ (11) Miami (FL) | 1:00 PM | |
| (FFO) Mississippi State @ (NFO) Florida | 1:00 PM | |
| (NFO) Villanova @ Xavier | 1:00 PM | |
| Saint Louis @ (11) Richmond | 1:00 PM | |
| (3) LSU @ (2) Texas | 2:00 PM | ABC |
| (10) TCU @ (8) Arizona | 3:00 PM | |
| (FFO) Vanderbilt @ (10) Auburn | 3:00 PM | SEC Network |
| Boston College @ (2) Stanford | 4:00 PM | |
| (5) Nebraska @ (FFO) Illinois | 4:00 PM | BTN |
| (FFO) Syracuse @ (NFO) California | 5:00 PM | ACC Network |
| (2) USC @ (9) Washington | 6:00 PM | BTN |
| (4) Michigan State @ (2) UCLA | 8:00 PM | BTN |
| Santa Clara @ (10) Oregon State | 0:00 | |
| (9) North Carolina @ (FFO) Syracuse | 5:00 PM | ACC Network |
| Pittsburgh @ (9) Florida State | 5:00 PM | |
| (7) Alabama @ (7) Tennessee | 5:30 PM | |
| Arkansas @ (1) South Carolina | 6:00 PM | SEC Network |
| (1) Notre Dame @ (11) Miami (FL) | 6:00 PM | |
| (3) Ohio State @ (5) Indiana | 6:00 PM | Peacock |
| (8) Louisville @ (3) Duke | 6:00 PM | ESPN2 |
| (4) North Carolina State @ Georgia Tech | 6:00 PM | |
| (FFO) Vanderbilt @ (6) Oklahoma | 6:00 PM | |
| (NFO) California @ Virginia | 6:00 PM | |
 Southern Illinois @ (12) Drake | 6:00 PM | |
| (4) Maryland @ Northwestern | 6:30 PM | BTN |
| (11) Middle Tennessee @ Louisiana Tech | 6:30 PM | ESPN+ |
| (2) Stanford @ (4) Virginia Tech | 7:00 PM | ACC Network |
| (NFO) Florida @ (11) Texas A&M | 7:00 PM | |
| Georgia @ (3) LSU | 8:00 PM | SEC Network |
| Saint Mary's College @ (7) Gonzaga | 8:00 PM | |
| Rutgers @ (9) Washington | 8:00 PM | |
| San Francisco @ (10) Washington State | 8:00 PM | |
| (FFO) Illinois @ (2) UCLA | 8:30 PM | BTN |
| (6) Penn State @ (10) Michigan | 11:00 AM | BTN |
| Milwaukee @ (12) Green Bay | 1:00 PM | |
| (7) Iowa State @ (6) Baylor | 1:30 PM | FOX |
| (5) Colorado @ (NFO) Oklahoma State | 2:00 PM | |
| Saint Mary's College @ (10) Washington State | 2:00 PM | |
| (11) UNLV @ Colorado State | 2:00 PM | |
| (11) Middle Tennessee @ Sam Houston State | 2:00 PM | ESPN+ |
| (12) South Dakota State @ UMKC | 2:00 PM | |
| Missouri State @ (12) Drake | 2:00 PM | |
| (1) Connecticut @ Butler | 3:30 PM | SNY |
| (9) Kansas @ (3) Kansas State | 4:00 PM | |
| San Francisco @ (7) Gonzaga | 4:00 PM | |
| San Diego @ (10) Oregon State | 4:00 PM | |
| (12) Columbia @ Princeton | 4:30 PM | |
| (8) Arizona @ Houston | 7:00 PM | |
| (1) Notre Dame @ (4) North Carolina State | 11:00 AM | ESPN |
| Purdue @ (3) Ohio State | 11:00 AM | BTN |
| (6) West Virginia @ (10) TCU | 11:00 AM | ESPN2 |
| Wake Forest @ (11) Miami (FL) | 11:00 AM | ACC Network |
| (NFO) Villanova @ Providence | 11:00 AM | FS1 |
| (7) Tennessee @ (NFO) Florida | 12:00 PM | SEC Network |
| (11) Richmond @ VCU | 12:00 PM | |
| (2) UCLA @ (1) Iowa | 1:00 PM | Peacock |
| (FFO) Syracuse @ (3) Duke | 1:00 PM | |
| (5) Indiana @ (4) Michigan State | 1:00 PM | BTN |
| (NFO) California @ (4) Virginia Tech | 1:00 PM | ACC Network |
| (5) Utah @ Cincinnati | 1:00 PM | |
| (9) North Carolina @ (8) Louisville | 1:00 PM | ESPN |
| (9) Florida State @ Georgia Tech | 1:00 PM | |
| (1) South Carolina @ (FFO) Vanderbilt | 2:00 PM | |
| (9) Washington @ (5) Nebraska | 2:00 PM | |
| (6) Oklahoma @ Arkansas | 2:00 PM | |
| Missouri @ (8) Ole Miss | 2:00 PM | SEC Network |
| (8) Creighton @ DePaul | 2:00 PM | |
| (11) Texas A&M @ (FFO) Mississippi State | 2:00 PM | |
| (FFO) Illinois @ (2) USC | 3:00 PM | FS1 |
| (3) LSU @ Kentucky | 3:00 PM | ESPN |
| (10) Auburn @ (7) Alabama | 4:00 PM | SEC Network |
| (2) Stanford @ Virginia | 5:00 PM | ACC Network |
| (10) Washington State @ Pepperdine | 3:00 PM | |
| Purdue @ (6) Penn State | 5:00 PM | BTN |
| Clemson @ (8) Louisville | 5:00 PM | ACC Network |
| (10) Auburn @ Georgia | 5:00 PM | |
| (8) Creighton @ (1) Connecticut | 6:00 PM | CBSSN |
| (9) North Carolina @ (3) Duke | 6:00 PM | ESPN |
| Wake Forest @ (4) North Carolina State | 6:00 PM | |
| (4) Maryland @ (5) Indiana | 6:00 PM | Peacock |
| (4) Virginia Tech @ Boston College | 6:00 PM | |
| (6) Oklahoma @ (NFO) Florida | 6:00 PM | |
| (7) Tennessee @ Kentucky | 6:00 PM | SEC Network |
| Pittsburgh @ (FFO) Syracuse | 6:00 PM | |
 Indiana State @ (12) Drake | 6:00 PM | |
| (2) Texas @ (FFO) Mississippi State | 6:30 PM | |
| (11) Texas A&M @ (FFO) Vanderbilt | 6:30 PM | |
| New Mexico State @ (11) Middle Tennessee | 6:30 PM | ESPN+ |
| (9) Florida State @ (1) Notre Dame | 7:00 PM | ACC Network |
| Denver @ (12) South Dakota State | 7:00 PM | |
| (1) South Carolina @ (8) Ole Miss | 8:00 PM | |
| (3) LSU @ (7) Alabama | 8:00 PM | |
| (7) Gonzaga @ Pacific | 8:00 PM | |
| (10) Oregon State @ Saint Mary's College | 8:30 PM | |
| (11) Miami (FL) @ (2) Stanford | 9:00 PM | |
| Georgia Tech @ (NFO) California | 9:00 PM | |
| Minnesota @ (4) Michigan State | 1:00 PM | |
| (6) West Virginia @ Cincinnati | 1:00 PM | |
 UTEP @ (11) Middle Tennessee | 1:00 PM | ESPN+ |
| (11) Richmond @ Saint Joseph's | 1:00 PM | |
| Yale @ (12) Columbia | 1:00 PM | |
| Purdue Fort Wayne @ (12) Green Bay | 1:00 PM | |
| (5) Colorado @ Texas Tech | 2:00 PM | |
| Saint Thomas @ (12) South Dakota State | 2:00 PM | |
| (12) Drake @ Northern Iowa | 2:00 PM | |
| BYU @ (5) Utah | 2:30 PM | |
| (10) Oregon State @ Pepperdine | 3:00 PM | |
| (7) Gonzaga @ Santa Clara | 4:00 PM | |
 San Jose State @ (11) UNLV | 4:00 PM | |
| (8) Arizona @ Arizona State | 5:00 PM | |
| (2) USC @ (2) UCLA | 8:00 PM | FOX |
| Oregon @ (9) Washington | 0:00 | |
| (8) Louisville @ (1) Notre Dame | 11:00 AM | ESPN |
| (4) North Carolina State @ SMU | 11:00 AM | ACC Network |
| Georgia @ (7) Tennessee | 11:00 AM | SEC Network |
| Kentucky @ (1) South Carolina | 1:00 PM | ESPN |
| (NFO) Florida @ (2) Texas | 1:00 PM | SEC Network |
| (4) Virginia Tech @ Clemson | 1:00 PM | ACC Network |
| (5) Indiana @ Purdue | 1:00 PM | Peacock |
| (6) Penn State @ Rutgers | 1:00 PM | |
| Virginia @ (9) North Carolina | 1:00 PM | |
| Marquette @ (1) Connecticut | 1:30 PM | FOX |
| (7) Alabama @ (6) Oklahoma | 1:30 PM | |
| (5) Nebraska @ Northwestern | 2:00 PM | |
| (NFO) Oklahoma State @ (9) Kansas | 2:00 PM | |
| (10) Michigan @ (FFO) Illinois | 2:00 PM | |
| (FFO) Mississippi State @ (10) Auburn | 2:00 PM | |
| Arkansas @ (11) Texas A&M | 2:00 PM | |
| Missouri @ (FFO) Vanderbilt | 2:00 PM | |
| Wisconsin @ (1) Iowa | 3:00 PM | Peacock |
| (8) Ole Miss @ (3) LSU | 3:00 PM | SEC Network |
| (3) Kansas State @ (7) Iowa State | 3:00 PM | ESPN2 |
| Boston College @ (FFO) Syracuse | 3:00 PM | ACC Network |
| Georgia Tech @ (2) Stanford | 4:00 PM | |
| (3) Ohio State @ (4) Maryland | 4:00 PM | FOX |
| (11) Miami (FL) @ (NFO) California | 4:00 PM | |
| (3) Duke @ (9) Florida State | 5:00 PM | ACC Network |
| (10) TCU @ (6) Baylor | 5:30 PM | FS1 |
| (NFO) Villanova @ (8) Creighton | 7:30 PM | FS1 |
Incarnate Word @ (10) 
Cal State Fullerton @ (9) 
Coastal Carolina @ (4) 
Morehead State @ (8) 
Rice @ (7) 
Southern Miss
Ball State
Florida A&M
Maryland Eastern Shore
Western Carolina @ (7) 
Utah Tech
Maine @ (5) 
Toledo
Hawaii
Georgia State @ (7) 
Canisius
Hofstra @ (NFO) 
Seattle University @ (8) 
Tennessee Tech @ (5) 
Holy Cross @ (1) 
Mount Saint Mary's @ (4) 
Lindenwood @ (5) 
California Baptist @ (2) 
East Tennessee State @ (6) 
Cal State Bakersfield @ (8) 
Delaware
UNCG @ (9) 
UTSA @ (2) 
McNeese @ (NFO) 
Weber State @ (8) 
ULM
La Salle @ (2) 
North Dakota State @ (9) 
Binghamton
Akron
Loyola-Maryland @ (1) 
Alcorn State @ (8) 
Saint Bonaventure @ (11) 
Air Force @ (11) 
George Washington @ (11)